Deck 14: Enzymes As Biological Catalysts

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Question
What does lactase do?

A) metabolizes lactose into carbon dioxide and water
B) hydrolyzes lactose into smaller sugars, glucose and galactose
C) synthesizes lactose in the body
D) removes lactose from the body
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Question
The purpose of an enzyme is to

A) transport nutrients through the body.
B) provide structure, such as hair or cell walls.
C) speed the rate of a chemical reaction.
D) transport oxygen throughout the body.
Question
Which of the following describes reaction energy?

A) the energy difference between the reactants and transition state
B) the energy difference between the transition state and products
C) the energy possessed by the reactants
D) the energy difference between the products and reactants
Question
Activation energy is the energy input that is required to form the

A) reactants.
B) transition state.
C) products.
D) all of the above
Question
In the reaction CH3Br + OH- \rightarrow CH3OH + Br-, what is the hypothesized shape of the transition state?

A) tetrahedral
B) trigonal planar
C) trigonal bipyramidal
D) octahedral
Question
In the reaction CH3Br + OH- \rightarrow CH3OH + Br-, what is the shape of the CH3Br?

A) tetrahedral
B) trigonal planar
C) trigonal bipyramidal
D) octahedral
Question
A catalyst increases the rate of a chemical reaction by

A) decreasing the reaction energy.
B) increasing the energy of the reactants.
C) decreasing the energy of the products.
D) decreasing the activation energy.
Question
What is the substance produced by the catalytic converter in your car when carbon monoxide, CO, passes through it?

A) methane, CH4
B) carbonate, CO32-
C) carbon dioxide, CO2
D) carbon, C
Question
What is the catalyst coating on the inside of a catalytic converter?

A) activated carbon
B) stainless steel
C) transition metals
D) magnesium
Question
Why are the transition metals good catalysts?

A) They can form positive ions.
B) They react readily with carbon monoxide.
C) They can readily change oxidation state and absorb other substances on to their surface and activate them toward other reactions.
D) They are good conductors of heat.
Question
The catalytic activity of an enzyme occurs where?

A) at the cofactor
B) at the active site
C) on the substrate
D) anywhere on the enzyme
Question
What are most enzymes?

A) metal ions
B) vitamins
C) minerals
D) proteins with a specific structure
Question
What substance does lactase use to catalyze the hydrolysis of lactose?

A) H2O
B) HCl
C) H2O2
D) NaOH
Question
What is missing in people who are lactose intolerant?

A) vitamin K
B) lactase
C) bacteria in their intestines
D) protease
Question
What causes the production of lactase in people who are lactose tolerant?

A) The transcription factor does not bind to the promoter site.
B) The transcription factor binds to the promoter site.
C) The mRNA carrying the gene can't leave the cell nucleus.
D) An incorrect amino acid is used during translation.
Question
What historical event may have selected for people who are lactose tolerant?

A) raising cows and goats to make cheese
B) hunting for meat
C) famine causing dairy farmers to drink milk
D) farming grains, such as wheat and barley
Question
What are ribozymes?

A) protein enzymes
B) RNA enzymes
C) DNA enzymes
D) substance that translates amino acids into protein enzymes
Question
Alpha Centauri is a star that is 4.37 light-years away. A rocket ship travelling at the speed of light would require 2,300,000 minutes to reach the star. If the rocket ship traveled at a speed 1 million times faster than the speed of light, how many minutes would it take the rocket ship to reach Alpha Centauri?

A) 2.3 minutes
B) 2300 minutes
C) 0.23 minutes
D) 23 minutes
Question
An auxiliary molecule that some enzymes require to carry out their function is called a(an)

A) substrate.
B) cofactor.
C) active site.
D) transition state.
Question
In the induced-fit model of the enzyme function, what is changing shape?

A) the substrate only
B) the enzyme only
C) both the substrate and enzyme
D) neither the substrate or enzyme
Question
How does gene-culture co-evolution explain lactase persistence in some adult populations in the world?

A) It was an advantage to be lactose tolerant to consume cheese.
B) Milk which was drunk in times of famine caused a mutation in the lactase gene.
C) Adults who were able to consume milk survived better in famines and so had a selective advantage.
D) Over time some populations developed bacteria in the gut that consume lactose.
Question
Why are lactose intolerant people incapable of producing lactase?

A) The gene that expresses lactase is missing.
B) Transcription factor binds to the promoter site and does not express lactase.
C) Transcription factor does not bind to the promoter site and does not express lactase.
D) The RNA that is transcribed from the lactose gene fails to translate amino acids into lactase.
Question
Lactase persistence is the

A) ability of babies and infants to produce lactase.
B) inability of adults to produce lactase.
C) switch from being able to produce lactase to not producing lactase.
D) the ability for some adults to produce lactase.
Question
How does lactose intolerance vary in global geography?

A) Lactose intolerance is common in people in all parts of the globe.
B) Lactose intolerance is common in Northern Europe.
C) Lactose intolerance is common in East Asia.
D) Lactose intolerance is not common in any part of the globe.
Question
Activation energy refers to what energy in the reaction pathway?

A) the energy of the reactants
B) the difference in energy between the transition state and the products
C) the difference in energy between products and reactants
D) the difference in energy between the transition state and the reactants.
Question
A catalyst affects which energy?

A) the energy of the reactants
B) the energy of the products
C) the reaction energy
D) the activation energy
Question
Which energy is required to be input to complete a reaction?

A) the energy of the reactants
B) the energy of the products
C) the reaction energy
D) the activation energy
Question
The catalyst in the catalytic converter accelerates the rate of the reaction C≡O + O=O \rightarrow O=C=O + O. How does it accomplish this?

A) It mixes carbon monoxide and oxygen.
B) It creates a turbulent mixing of carbon monoxide and oxygen.
C) It raises the temperature of the carbon monoxide and oxygen.
D) It lowers the energy barrier between the carbon monoxide/oxygen reactants and the carbon dioxide/oxygen products.
Question
According to the naming convention, which of the following is likely an enzyme?

A) amylose
B) amylase
C) galactose
D) amyloid
Question
Other than proteins, what other biochemical may act as a catalyst?

A) DNA
B) polysaccharides
C) vitamins
D) RNA
Question
Which of the following is a correct assumption made for the lock-and-key model of enzymes?

A) Both the enzyme and substrate are flexible in shape.
B) The enzyme is flexible while the substrate shape is rigid.
C) Both the enzyme and substrate are rigid in shape.
D) The substrate shape is flexible while the enzyme shape is rigid.
Question
A catalyst is consumed or altered when it is used in a chemical reaction.
Question
A catalyst can accelerate hundreds, thousands, or millions of individual reactions.
Question
A transition metal catalyst speeds up reactions more than an enzyme.
Question
All people carry the gene to produce lactase.
Question
An enzyme speeds up reactions billions or trillions of times greater than a metal catalyst.
Question
The shape of the active site on the enzyme determines the binding of the substrate.
Question
Enzymes are more selective in which substrates they bind than metal catalysts.
Question
Two very similar molecules that differ only in being chiral, such as D- or L-, will always bind similarly to an enzyme.
Question
People who are lactose intolerant cannot digest cheese which contains no lactose.
Question
Milk contains the protein lactase.
Question
A reaction component with higher potential energy is more stable.
Question
The energy barrier between reactants and products in a reaction is ____________________.
Question
The stages by which reactants are transformed into products is called ____________________.
Question
In the reaction of methyl bromide and hydroxide the orientation of the C-H bonds flips. This is called ____________________.
Question
The binding of substrate to an enzyme is the ____________________ model.
Question
The binding of a substrate to a catalyst where both components change shape is the ____________________ model.
Question
Catalysts operate through a series of steps called the ____________________.
Question
The sugars glucose and galactose are joined in lactose by ____________________ bonds.
Question
Describe the transition state for the reaction of methyl bromide and hydroxide.
Question
How does a catalyst lower the activation energy of a chemical reaction?
Question
Describe the steps of a catalytic cycle.
Question
What are the four complementary functional group interactions between the enzyme and substrate?
Question
Explain why you can't increase temperature to speed up a biological reaction.
Question
How is an enzyme capable of catalyzing more than one cycle of a reaction pathway?
Question
Explain how the induced-fit model of the enzyme allows the enzyme to catalyze reactions millions of times faster than a metal catalyst.
Question
Why would so few adults in East Asia be lactose tolerant?
Question
The Inuit, indigenous people of the Arctic, rely on fish, sea mammals, and land animals for food. Would you expect them to be lactose tolerant or lactose intolerant?
Question
What causes the symptoms experienced by lactose intolerant people who consume milk?
Question
Why are enzymes so highly selective in which substrates they bind?
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Deck 14: Enzymes As Biological Catalysts
1
What does lactase do?

A) metabolizes lactose into carbon dioxide and water
B) hydrolyzes lactose into smaller sugars, glucose and galactose
C) synthesizes lactose in the body
D) removes lactose from the body
B
2
The purpose of an enzyme is to

A) transport nutrients through the body.
B) provide structure, such as hair or cell walls.
C) speed the rate of a chemical reaction.
D) transport oxygen throughout the body.
C
3
Which of the following describes reaction energy?

A) the energy difference between the reactants and transition state
B) the energy difference between the transition state and products
C) the energy possessed by the reactants
D) the energy difference between the products and reactants
D
4
Activation energy is the energy input that is required to form the

A) reactants.
B) transition state.
C) products.
D) all of the above
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k this deck
5
In the reaction CH3Br + OH- \rightarrow CH3OH + Br-, what is the hypothesized shape of the transition state?

A) tetrahedral
B) trigonal planar
C) trigonal bipyramidal
D) octahedral
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Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
6
In the reaction CH3Br + OH- \rightarrow CH3OH + Br-, what is the shape of the CH3Br?

A) tetrahedral
B) trigonal planar
C) trigonal bipyramidal
D) octahedral
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Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
7
A catalyst increases the rate of a chemical reaction by

A) decreasing the reaction energy.
B) increasing the energy of the reactants.
C) decreasing the energy of the products.
D) decreasing the activation energy.
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Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
8
What is the substance produced by the catalytic converter in your car when carbon monoxide, CO, passes through it?

A) methane, CH4
B) carbonate, CO32-
C) carbon dioxide, CO2
D) carbon, C
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Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
9
What is the catalyst coating on the inside of a catalytic converter?

A) activated carbon
B) stainless steel
C) transition metals
D) magnesium
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
10
Why are the transition metals good catalysts?

A) They can form positive ions.
B) They react readily with carbon monoxide.
C) They can readily change oxidation state and absorb other substances on to their surface and activate them toward other reactions.
D) They are good conductors of heat.
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
11
The catalytic activity of an enzyme occurs where?

A) at the cofactor
B) at the active site
C) on the substrate
D) anywhere on the enzyme
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
12
What are most enzymes?

A) metal ions
B) vitamins
C) minerals
D) proteins with a specific structure
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
13
What substance does lactase use to catalyze the hydrolysis of lactose?

A) H2O
B) HCl
C) H2O2
D) NaOH
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
14
What is missing in people who are lactose intolerant?

A) vitamin K
B) lactase
C) bacteria in their intestines
D) protease
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
15
What causes the production of lactase in people who are lactose tolerant?

A) The transcription factor does not bind to the promoter site.
B) The transcription factor binds to the promoter site.
C) The mRNA carrying the gene can't leave the cell nucleus.
D) An incorrect amino acid is used during translation.
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
16
What historical event may have selected for people who are lactose tolerant?

A) raising cows and goats to make cheese
B) hunting for meat
C) famine causing dairy farmers to drink milk
D) farming grains, such as wheat and barley
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
17
What are ribozymes?

A) protein enzymes
B) RNA enzymes
C) DNA enzymes
D) substance that translates amino acids into protein enzymes
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
18
Alpha Centauri is a star that is 4.37 light-years away. A rocket ship travelling at the speed of light would require 2,300,000 minutes to reach the star. If the rocket ship traveled at a speed 1 million times faster than the speed of light, how many minutes would it take the rocket ship to reach Alpha Centauri?

A) 2.3 minutes
B) 2300 minutes
C) 0.23 minutes
D) 23 minutes
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
19
An auxiliary molecule that some enzymes require to carry out their function is called a(an)

A) substrate.
B) cofactor.
C) active site.
D) transition state.
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
20
In the induced-fit model of the enzyme function, what is changing shape?

A) the substrate only
B) the enzyme only
C) both the substrate and enzyme
D) neither the substrate or enzyme
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
21
How does gene-culture co-evolution explain lactase persistence in some adult populations in the world?

A) It was an advantage to be lactose tolerant to consume cheese.
B) Milk which was drunk in times of famine caused a mutation in the lactase gene.
C) Adults who were able to consume milk survived better in famines and so had a selective advantage.
D) Over time some populations developed bacteria in the gut that consume lactose.
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
22
Why are lactose intolerant people incapable of producing lactase?

A) The gene that expresses lactase is missing.
B) Transcription factor binds to the promoter site and does not express lactase.
C) Transcription factor does not bind to the promoter site and does not express lactase.
D) The RNA that is transcribed from the lactose gene fails to translate amino acids into lactase.
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
23
Lactase persistence is the

A) ability of babies and infants to produce lactase.
B) inability of adults to produce lactase.
C) switch from being able to produce lactase to not producing lactase.
D) the ability for some adults to produce lactase.
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
24
How does lactose intolerance vary in global geography?

A) Lactose intolerance is common in people in all parts of the globe.
B) Lactose intolerance is common in Northern Europe.
C) Lactose intolerance is common in East Asia.
D) Lactose intolerance is not common in any part of the globe.
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
25
Activation energy refers to what energy in the reaction pathway?

A) the energy of the reactants
B) the difference in energy between the transition state and the products
C) the difference in energy between products and reactants
D) the difference in energy between the transition state and the reactants.
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
26
A catalyst affects which energy?

A) the energy of the reactants
B) the energy of the products
C) the reaction energy
D) the activation energy
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
27
Which energy is required to be input to complete a reaction?

A) the energy of the reactants
B) the energy of the products
C) the reaction energy
D) the activation energy
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
28
The catalyst in the catalytic converter accelerates the rate of the reaction C≡O + O=O \rightarrow O=C=O + O. How does it accomplish this?

A) It mixes carbon monoxide and oxygen.
B) It creates a turbulent mixing of carbon monoxide and oxygen.
C) It raises the temperature of the carbon monoxide and oxygen.
D) It lowers the energy barrier between the carbon monoxide/oxygen reactants and the carbon dioxide/oxygen products.
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
29
According to the naming convention, which of the following is likely an enzyme?

A) amylose
B) amylase
C) galactose
D) amyloid
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
30
Other than proteins, what other biochemical may act as a catalyst?

A) DNA
B) polysaccharides
C) vitamins
D) RNA
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
31
Which of the following is a correct assumption made for the lock-and-key model of enzymes?

A) Both the enzyme and substrate are flexible in shape.
B) The enzyme is flexible while the substrate shape is rigid.
C) Both the enzyme and substrate are rigid in shape.
D) The substrate shape is flexible while the enzyme shape is rigid.
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
32
A catalyst is consumed or altered when it is used in a chemical reaction.
Unlock Deck
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Unlock Deck
k this deck
33
A catalyst can accelerate hundreds, thousands, or millions of individual reactions.
Unlock Deck
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Unlock Deck
k this deck
34
A transition metal catalyst speeds up reactions more than an enzyme.
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k this deck
35
All people carry the gene to produce lactase.
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Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
36
An enzyme speeds up reactions billions or trillions of times greater than a metal catalyst.
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
37
The shape of the active site on the enzyme determines the binding of the substrate.
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Unlock Deck
k this deck
38
Enzymes are more selective in which substrates they bind than metal catalysts.
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
39
Two very similar molecules that differ only in being chiral, such as D- or L-, will always bind similarly to an enzyme.
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Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
40
People who are lactose intolerant cannot digest cheese which contains no lactose.
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
41
Milk contains the protein lactase.
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
42
A reaction component with higher potential energy is more stable.
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Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
43
The energy barrier between reactants and products in a reaction is ____________________.
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k this deck
44
The stages by which reactants are transformed into products is called ____________________.
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Unlock Deck
k this deck
45
In the reaction of methyl bromide and hydroxide the orientation of the C-H bonds flips. This is called ____________________.
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Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
46
The binding of substrate to an enzyme is the ____________________ model.
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Unlock Deck
k this deck
47
The binding of a substrate to a catalyst where both components change shape is the ____________________ model.
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k this deck
48
Catalysts operate through a series of steps called the ____________________.
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k this deck
49
The sugars glucose and galactose are joined in lactose by ____________________ bonds.
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k this deck
50
Describe the transition state for the reaction of methyl bromide and hydroxide.
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51
How does a catalyst lower the activation energy of a chemical reaction?
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k this deck
52
Describe the steps of a catalytic cycle.
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53
What are the four complementary functional group interactions between the enzyme and substrate?
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k this deck
54
Explain why you can't increase temperature to speed up a biological reaction.
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k this deck
55
How is an enzyme capable of catalyzing more than one cycle of a reaction pathway?
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Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
56
Explain how the induced-fit model of the enzyme allows the enzyme to catalyze reactions millions of times faster than a metal catalyst.
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k this deck
57
Why would so few adults in East Asia be lactose tolerant?
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Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
58
The Inuit, indigenous people of the Arctic, rely on fish, sea mammals, and land animals for food. Would you expect them to be lactose tolerant or lactose intolerant?
Unlock Deck
Unlock for access to all 60 flashcards in this deck.
Unlock Deck
k this deck
59
What causes the symptoms experienced by lactose intolerant people who consume milk?
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60
Why are enzymes so highly selective in which substrates they bind?
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