Question 1

Therapists treating exercising patients on anti-psychotic agents should be especially concerned about which of the following?&#10;A)Impaired thermoregulation&#10;B)Prolactinemia&#10;C)Amenorrhea&#10;D)Agranulocytosis

Accepted Answer

While all of these items represent side effects of anti-psychotic agents,impaired thermoregulation possibly producing heat stroke is most significant for the therapist.

Question 2

Tardive dyskinesia is characterized by which of the following?&#10;A)Orthostatic hypotension&#10;B)Involuntary facial movements&#10;C)Spasms of the feet&#10;D)Collapse of the autonomic nervous system

Accepted Answer

Tardive dyskinesia is fly-swapping movements of the tongue that are not under voluntary control and is irreversible.

Question 3

Anti-psychotic agents may cause osteoporosis secondary to elevation of which of the following hormones?&#10;A)Thyroid releasing hormone&#10;B)Prolactin&#10;C)Cortisol&#10;D)Estrogen

Accepted Answer

Elevated prolactin levels occur with these drugs and lead to osteoporosis.Hyperparathyroidism also can occur which likewise leads to a reduction in bone density.

Question 4

Which of the following signs of Schizophrenia respond poorly to anti-psychotic agents?&#10;A)Hallucinations&#10;B)Flattened emotions&#10;C)Posturing&#10;D)Echopraxia

Accepted Answer

Antipsychotic agents are most effective against the positive symptoms of schizophrenia (visual,olfactory and auditory hallucinations; posturing,waxy flexibility,and echopraxia).

Question 5

Which of the following behaviors is the most likely to be eliminated by the typical antipsychotic drugs?&#10;A)Hallucinations&#10;B)Apathy&#10;C)Social withdrawal&#10;D)Flat affect

Accepted Answer

Antipsychotic drugs are most helpful in eliminating the positive symptoms of schizophrenia,like the hallucinations,as opposed to the negative symptoms of flat affect,apathy,and social withdrawal.

Question 6

Which one of the following is true regarding antipsychotics?&#10;A)They have a high affinity for dopamine receptors.&#10;B)They produce mania.&#10;C)They stimulate the chemoreceptor trigger zone to produce vomiting.&#10;D)They have cholinergic side effects.

Accepted Answer

Antipsychotic agents block dopamine receptors to reduce mania.They also are antiemetics.

Question 7

Which of the following drugs for biopolar disorder have the lowest therapeutic index?&#10;A)Lithium&#10;B)Valproate&#10;C)Carbamazepine&#10;D)Lamotrigine

Accepted Answer

Lithium has a low therapeutic index; signs of toxicity include nausea,vomiting,tremor,ataxia,dysarthria,confusion,and sedation.

Question 8

Treatment for tardive dyskinesia may include which of the following?&#10;A)Adding an anticholinergic agent&#10;B)Increasing the dose of the antipsychotic agent&#10;C)Eliminating all dopaminergic blockade&#10;D)Reducing GABAergic activity

Accepted Answer

TD is largely irreversibly but administration of an anticholinergic drug may reduce some of the symptoms.Increasing GABAergic activity and lowering the dose of the antipsychotic agent may also be helpful.

Question 9

Patients taking anti-psychotic medications are at risk for which of the following cardiac abnormalities?&#10;A)Congestive heart failure&#10;B)Prolonged Q-T syndrome&#10;C)Mitral valve stenosis&#10;D)Aortic stenosis

Accepted Answer

Many anti-psychotic agents produce electrical disturbances of the heart and include prolonged Q-T syndrome,tachycardia and torsades de pointes arrhythmia.

Question 10

Which of the following may be an irreversible adverse effect of neuroleptic agents?&#10;A)Parkinsonian syndrome&#10;B)Akathisia&#10;C)Tardive dyskinesia&#10;D)Neuroleptic malignant syndrome

Accepted Answer

Tardive dyskinesia,involuntary facial movements,particularly fly-swapping movements of the tongue,is frequently irreversible.

Deck 19: Drug Treatment for Schizophrenia and Bipolar Illness