Deck 5: Medical Topics

Question 1

Which of the following concerning diamorphine elixir for the relief of pain in terminal patients is corrcet?

A)Analgesia is enhanced if cocaine is added
B)Constipation is a characteristic sequel to treatment
C)Dependence occurs rapidly
D)initial sedation typically continues whilst the drug is administered
E)the same amount of pain relief is produced as when the same dose is given via intramuscular injection

Answer 1

Constipation is a characteristic sequel to treatment

Question 2

In a case of Dysgerminoma of ovary tumor markers is likely to be raised.one of the following

A)Serum HCG
B)Serum alphafetoprotein
C)Serum lactate dehydrogenase
D)Serum inhibin

Answer 2

Serum lactate dehydrogenase

Question 3

The most common pure germ cell tumor of the ovary is:

A)Chriocarcinoma
B)Dysgerminoma
C)Embryonoal cell tumor
D)Malignant Teratoma

Answer 3

Dysgerminoma

Question 4

The highest incidence of Gestational Trophoblastic Disease is in:

A)Australia
B)Asia
C)North America
D)Westem Europe

Question 5

According to the FIGO staging of gestational trophoblastic tumors, a lady with choriocarcinoma having lung metastasis will belong to which stage

A)l
B)ll
C)lll
D)lV

Question 6

A patient with non-metastatic gestational trophoblastic disease can be treated with weekly intramuscular injections of which of the following agents?

A)Cyclophosphamide
B)Carboplatin
C)Etoposide
D)Actinomycin
E)Methotrexate

Question 7

Five-year survival rates of patients with low-risk, non-metastatic gestational trophoblastic disease approaches?

A)100%
B)75%
C)50%
D)25%
E)5-10%

Question 8

Comparing complete hydatidiform moles gestations, complete hydatidiform mole gestations are more likely than partial moles to demonstrate all of these characteristics except?

A)More likely to require chemotherapy after evacuation for gestational trophablastic disease
B)more likely to present with a uterus large for dates
C)more likely to present with theca lutein cysts
D)more likely to 'have focal rather than diffuse trophoblastic proliferation
E)more likely to have diffuse hydopic swelling of villi

Question 9

A woman experiencing a molar pregnancy has an increased risk of which of the following in subsequent gestations ?

A)Stillbirth
B)Prematurity
C)Congenital malformations
D)Recurrent molar gestation
E)Cancer later in life

Question 10

The most likely karyotype of patient with a complete mole would be ?

A)46, XX
B)46, XY
C)Diandric triploidy
D)Triploidy with two haploid sets of maternal origin
E)Aneuploidy

Question 11

The most likely karyotype for patient with a partial mole would be ?

A)46, XX
B)46, XY
C)Diandric triploidy
D)Triploidy with two haploid sets of maternal origin
E)Aneuploidy

Question 12

A woman with a complete mole is most likely to present with which of the symptoms?

A)Vaginal Bleeding
B)Excessive uterine size
C)Hypermesis
D)Pre-eclampsia
E)Prominent theca lutein cysts

Question 13

A patient with a complete mole is found to have sizeable ovarian cysts that are presumed to be theca lutein cysts. All of the following are true about theca lutein cysts EXCEPT?

A)Such cysts arise more frequently in patients with complete moles
B)Theca lutein cysts are more likely seen in patients with very high hCG levels
C)Cysts are filled with serious or serosanguinous fluid and are usually bilateral
D)Often require active management with surgical intervention
E)Patients with large theca lutein cysts may be at increased risk for postmolar persistence of disease

Question 14

Regarding gestational trophoblastic disease (GTD),all are true except

A)Incomplete moles are more likely to undergo malignant change than the complete moles
B)GTD is almost always completely curable with preservation of fertility
C)Lymphnode involvement is a rare feature of choriocarcinoma
D)GTD usually shows low resistance blood flow
E)It is rare to have other metastasis in the absence of lung metastasis

Question 15

Risk of Malignancy in Adenomatous polyp is related to all except

A)Size
B)Number
C)Histological appearance
D)Dysplasia

Question 16

Polyps are generally managed endoscopically. Which of the following is not an indication for resectional surgery

A)Lymphovascular invasion
B)Poor differentiation
C)Flat or ulcerated lesion
D)Lesion in upper 1/3rd of submucosa

Question 17

Which of the following is not true for malignancy of Familial Adenomatous Polyposis

A)Adrenals
B)Thyroid
C)Astrocytomas
D)Hepatoblastomas

Question 18

What is not true for HNPCC

A)It is the most common hereditary colorectal cancer syndrome in USA
B)It is associated with MMR gene mutation
C)It is associated with APC mutation
D)It is associated with carcinoma colon and extraintestinal cancers
E)Answer C and D are correct

Question 19

True about Ulcerative Colitis with malignancy

A)It has a better prognosis
B)Is related to disease activity
C)Is related to duration of ulcerative colitis
D)Malignancy is more in anorectal ulcerative colitis
E)All of above

Question 20

In ulcerative coilitis with toxic megacolon lowest rate of recurrence is seen in

A)Complete proctocolectomy and Brook's ileostomy
B)Ileo rectal anastomoses
C)kock's pouch
D)none of above

Question 21

All are precancerous for carcinoma colon except

A)Crohn's disease
B)Bile acids
C)Fats
D)Carotene

Question 22

Which of these genetic risk factors has the highest association with colon cancers

A)Sporadic
B)Past family history of colo rectal cancer
C)Hereditary Nonpolyposis colon cancer (HNPCC)
D)Familial Adenomatous Polyposis (FAP)

Question 23

After total proctocolectomy with ileal pouch anal anastomoses what is the most common cause of death in patients with Familial Adenomatous Polyposis (FAP)

A)Gastric cancer
B)Periampullary carcinoma
C)Genito urinary cancers
D)Recurrence of colorectal cancer

Question 24

Most valuable investigation for preoperative evaluation of extensive corrosive stricture is

A)Endoscopic ultrasound
B)Barium study
C)CT Thorax
D)Pharyngoscopy

Question 25

Not an association between (PSC) Primary sclerosing cholangitis and Ulcerative colitis (UC)

A)Inflammatory Bowel disease (IBD) seen in 70% of patients with PSC
B)Diagnosis of IBD occurs 8-10 years before PSC
C)Colitis is severe in patients with both PSC And UC as compared to UC alone
D)Risk of colon cancer is more when patients have both UC and PSC as compared to UC alone