Deck 1: Introduction to Pharmacology

Question 1

Which endeavor is most important for determining the dose-response relationship of a drug?

A) isolation of a pure drug compound
B) measurement of the plasma concentration of a drug over time
C) clinical trials to determine drug efficacy
D) study of the structure-activity relationship of a drug
E) development of a sustained-release formulation of a drug

Answer 1

isolation of a pure drug compound

Question 2

A patient is administered a drug in the form of a tablet formulated with an osmotic substance that slowly attracts water. Which characteristic is associated with this preparation?

A) used to treat constipation
B) enables almost 100% bioavailability
C) poses more risks than intramuscular administration
D) causes a localized effect on the colon
E) provides sustained drug absorption over many hours

Answer 2

provides sustained drug absorption over many hours