Deck 12: Drugs for Heart Failure

Question 1

Several weeks after beginning treatment for severe heart failure, a man develops hyperkalemia requiring hospitalization.
Which agent is most likely responsible for this adverse effect?

A) eplerenone
B) digoxin
C) furosemide
D) dobutamine
E) milrinone

Answer 1

eplerenone

Question 2

A patient with decompensated heart failure is given an intravenous infusion of a peptide drug. Which effect is produced by this treatment?

A) decreased synthesis of angiotensin II
B) blockade of angiotensin II receptors
C) increased levels of cyclic AMP
D) increased levels of cyclic GMP
E) increased influx of calcium

Answer 2

increased levels of cyclic GMP

Question 3

The beneficial effects of carvedilol in persons with heart failure are obtained with the use of which drug administration regimen?

A) intravenous infusion for 3 to 7 days
B) low doses that are gradually increased over time
C) loading doses followed by maintenance doses
D) high doses that are gradually tapered over time
E) titration to obtain the desired increase in cardiac output

Answer 3

low doses that are gradually increased over time