Deck 24: Antiviral, Antifungal, and Anti-Protozoal Agents

Question 1

The genetic information of viruses includes which of the following?

A) DNA
B) RNA
C) either DNA or RNA
D) none of the above

Answer 1

either DNA or RNA

Question 2

Which of the following is an example of emerging viruses that threaten the public health and may kill thousands of people each year?

A) dengue virus
B) herpes simplex virus
C) hepatitis A virus
D) varicella-zoster virus

Answer 2

dengue virus

Question 3

Acyclovir is most effective against which of the following viruses?

A) cytomegalovirus
B) varicella-zoster virus
C) herpes simplex virus
D) influenza A virus

Answer 3

herpes simplex virus

Question 4

Famciclovir is used for the management of which of the following viral disorders?

A) herpes zoster (shingles)
B) genital herpes
C) influenza
D) A and B

Question 5

Amantadine is used for which of the following disorders?

A) influenza A
B) influenza B
C) shingles
D) genital herpes

Question 6

Which of the following agents is a nonnucleoside reverse transcriptase inhibitor that prevents replication of HIV-1 virus?

A) zidovudine
B) amantadine
C) delavirdine
D) acyclovir

Question 7

Lamivudine is in which of the following classes of drugs used to treat HIV infection in patients with AIDS?

A) nucleoside reverse transcriptase inhibitors (NRTIs)
B) non-nucleoside reverse transcriptase inhibitors (NNRTIs)
C) protease Inhibitors (PIs)
D) miscellaneous drugs

Question 8

Ritonavir is an example of the:

A) NRTIs
B) NNRTIs
C) PIs
D) none of the above

Question 9

The fungi are a distinct group of organisms that are:

A) plants
B) animals
C) either plants or animals
D) neither plants nor animals

Question 10

Amphotericin B acts by binding to fungal:

A) cell membranes
B) nuclei
C) nucleotides
D) none of the above

Question 11

Which of the following is the most serious adverse effect of amphotericin B?

A) hepatotoxicity
B) nephrotoxicity
C) hypotension
D) hypertension

Question 12

Griseofulvin is available for which of the following routes of administration?

A) only the oral form
B) only the parenteral form
C) only the topical form
D) all of the above

Question 13

Vaginal tablets of nystatin are contraindicated in which of the following conditions or disorders?

A) pregnancy
B) vaginal infections caused by candida albicans
C) vaginal infections caused by Trichomonas species
D) A and C

Question 14

Ketoconazole is used for severe systemic fungal infections including:

A) candidiasis (oral thrush)
B) chronic mucocutaneous candidiasis
C) pulmonary candidiasis
D) all of the above

Question 15

Griseofulvin is effective in which of the following fungal infections?

A) yeast infections
B) candida infections
C) diaper rash
D) mycotic skin infections

Question 16

Which of the following is classified as an anti-protozoal?

A) rifampin
B) metronidazole
C) amantadine
D) nizatidine

Question 17

Itraconazole is an antifungal indicated in the treatment of which of the following infections?

A) blastomycosis
B) histoplasmosis
C) aspergillosis
D) all of the above

Question 18

Which of the following agents is an antimalarial?

A) metronidazole
B) primaquine
C) sulfamethoxazole
D) saquinavir

Question 19

Chloroquine is the drug of choice to treat acute malaria attacks resulting from which of the following plasmodium?

A) P. falciparum
B) P. vivax
C) P. ovale
D) all of the above

Question 20

Griseofulvin is classified as:

A) an antifungal
B) an antibiotic
C) an anti-infective
D) all of the above

Question 21

The process of the copying of genetic material is referred to as ____________________.

Question 22

Some animal viruses are responsible for diseases such as hemorrhagic fever caused by ____________________ virus.

Question 23

"Immunocompromised" means impairment of the ____________________.

Question 24

Amantadine is an antiviral and anticholinergic agent effective against influenza A and ____________________ disease.

Question 25

Ganciclovir should not be administered during pregnancy because of its ____________________ potential.

Question 26

Missing a single dose of HAART medication even twice a week can cause the development of drug-resistant ____________________.

Question 27

Lamuvidine is used for HIV infection in combination with ____________________.

Question 28

Fungi infections include athlete's foot, histoplasmosis, cryptococcosis, tinea, and ____________________ infections.

Question 29

Amphotericin B for parenteral use should only be mixed in ____________________.

Question 30

Chloroquine is the drug of choice to suppress ____________________ symptoms.

Question 31

An outbreak of infectious disease is called an __________.

Question 32

An inactive or partially active drug that is metabolically changed in the body to an active drug, is called a __________ - __________.

Question 33

Acyclovir is used against __________ viruses.

Question 34

Famciclovir is used for the management of acute herpes __________.

Question 35

Highly Active Anti-Retroviral Therapy (HAART) has been shown to reduce viral load and increase CD4 __________ in persons infected with HIV.

Question 36

Ritonavir is an anti-HIV drug that is a __________ inhibitor.

Question 37

Griseofulvin is effective in __________ infections of the nails, hair, and skin.

Question 38

Antiprotozoal drugs fall into two main categories. One is __________ and another is trichomonacides.

Question 39

Metronidazole is the drug of choice in amebic dysentery, giardiasis, and __________.

Question 40

Chloroquine, primaquine, and quinine are used to treat __________.

Question 41

Match the generic name with the trade name.

-didanosine

A) Zovirax
B) Symmetrel
C) Famvir
D) Cytovene
E) Vistide
F) Rebetol
G) Flumadine
H) Viramune
I) Crixivan
J) Videx

Question 42

Match the generic name with the trade name.

-ribavirin

A) Zovirax
B) Symmetrel
C) Famvir
D) Cytovene
E) Vistide
F) Rebetol
G) Flumadine
H) Viramune
I) Crixivan
J) Videx

Question 43

Match the generic name with the trade name.

-indinavir

A) Zovirax
B) Symmetrel
C) Famvir
D) Cytovene
E) Vistide
F) Rebetol
G) Flumadine
H) Viramune
I) Crixivan
J) Videx

Question 44

Match the generic name with the trade name.

-nevirapine

A) Zovirax
B) Symmetrel
C) Famvir
D) Cytovene
E) Vistide
F) Rebetol
G) Flumadine
H) Viramune
I) Crixivan
J) Videx

Question 45

Match the generic name with the trade name.

-rimantadine

A) Zovirax
B) Symmetrel
C) Famvir
D) Cytovene
E) Vistide
F) Rebetol
G) Flumadine
H) Viramune
I) Crixivan
J) Videx

Question 46

Match the generic name with the trade name.

-acyclovir

A) Zovirax
B) Symmetrel
C) Famvir
D) Cytovene
E) Vistide
F) Rebetol
G) Flumadine
H) Viramune
I) Crixivan
J) Videx

Question 47

Match the generic name with the trade name.

-cidofovir

A) Zovirax
B) Symmetrel
C) Famvir
D) Cytovene
E) Vistide
F) Rebetol
G) Flumadine
H) Viramune
I) Crixivan
J) Videx

Question 48

Match the generic name with the trade name.

-ganciclovir

A) Zovirax
B) Symmetrel
C) Famvir
D) Cytovene
E) Vistide
F) Rebetol
G) Flumadine
H) Viramune
I) Crixivan
J) Videx

Question 49

Match the generic name with the trade name.

-famciclovir

A) Zovirax
B) Symmetrel
C) Famvir
D) Cytovene
E) Vistide
F) Rebetol
G) Flumadine
H) Viramune
I) Crixivan
J) Videx

Question 50

Match the generic name with the trade name.

-amantadine

A) Zovirax
B) Symmetrel
C) Famvir
D) Cytovene
E) Vistide
F) Rebetol
G) Flumadine
H) Viramune
I) Crixivan
J) Videx

Question 51

Match the generic name with the trade name.

-atovaquone

A) Flagyl
B) Nebupent
C) Aralen
D) Lariam
E) Plaquenil
F) Mepron

Question 52

Match the generic name with the trade name.

-mefloquine

A) Flagyl
B) Nebupent
C) Aralen
D) Lariam
E) Plaquenil
F) Mepron

Question 53

Match the generic name with the trade name.

-hydroxychloroquine

A) Flagyl
B) Nebupent
C) Aralen
D) Lariam
E) Plaquenil
F) Mepron

Question 54

Match the generic name with the trade name.

-metronidazole

A) Flagyl
B) Nebupent
C) Aralen
D) Lariam
E) Plaquenil
F) Mepron

Question 55

Match the generic name with the trade name.

-chloroquine

A) Flagyl
B) Nebupent
C) Aralen
D) Lariam
E) Plaquenil
F) Mepron

Question 56

Match the generic name with the trade name.

-pentamidine

A) Flagyl
B) Nebupent
C) Aralen
D) Lariam
E) Plaquenil
F) Mepron