Deck 15: Anticoagulant Drugs

Question 1

A process that stops bleeding in a blood vessel is referred to as:

A) hemopathy
B) hemopoiesis
C) hemostasis
D) hemostat

Answer 1

hemostasis

Question 2

Prothrombin is produced by which of the following?

A) bone marrow
B) lungs
C) kidneys
D) liver

Answer 2

liver

Question 3

Which of the following substances causes clotting?

A) thromboplastin
B) thrombolytic
C) thrombin
D) heparin

Answer 3

thromboplastin

Question 4

The immediate response of a blood vessel to injury is:

A) vasodilation and the release of epinephrine
B) vasoconstriction and the release of thromboplastin
C) vasoconstriction and the release of serotonin
D) none of the above

Question 5

A thrombus that forms spontaneously in a vein without prior inflammation is called:

A) phlebitis
B) phlebothrombosis
C) thrombocytopenia
D) thrombophlebitis

Question 6

Which of the following anticoagulants is naturally obtained in the body?

A) warfarin
B) abciximab
C) heparin
D) ticlopidine

Question 7

Which of the following are the drugs of choice for many clotting disorders?

A) beta adrenergic blockers
B) ADP receptor blockers
C) glycoprotein II beta receptor blockers
D) low molecular weight heparins

Question 8

Warfarin is structurally similar to:

A) vitamin K
B) heparin
C) aspirin
D) urokinase

Question 9

Which of the following is a thrombolytic drug?

A) streptokinase
B) aspirin
C) abciximab
D) warfarin

Question 10

Which of the following is the major complication of heparin administration?

A) coronary occlusion
B) atrial fibrillation
C) spontaneous bleeding
D) myocardial infarction

Question 11

Which of the following adhere to thrombin and collagen?

A) platelets
B) polyneuclars
C) the surface of erythrocytes
D) none of the above

Question 12

Which of the following is a plasma protein?

A) thrombin
B) thrombus
C) fibrinogen
D) fibrosis

Question 13

Heparin can be inactivated by which of the following body fluids?

A) saliva and mucus in the mouth
B) hydrochloric acid in the stomach
C) pepsin in the stomach
D) none of the above

Question 14

The onset of action of oral heparin is:

A) immediate
B) within an hour
C) within four hours
D) none of the above

Question 15

After initiation of anticoagulant therapy with heparin, oral anticoagulants can be started after about:

A) 18 hours
B) 48 hours
C) 96 hours
D) one week

Question 16

Heparin therapy requires caution in patients with:

A) cerebral embolism
B) coronary occlusion
C) myocardial infarction
D) all of the above

Question 17

Antiplatelet agents are used to suppress clumping of:

A) erythrocytes
B) plasma cells
C) thrombocytes
D) all of the above

Question 18

Abciximab is used with heparin and aspirin to prevent:

A) pulmonary edema
B) myocarditis
C) cerebral embolism
D) coronary vessel occlusion in patients undergoing coronary angioplasty

Question 19

Which of the following agents dissolve existing clots?

A) thrombogenics
B) thrombolytics
C) antiplatelets
D) all of the above

Question 20

All of the following are thrombolytic drugs, except:

A) urokinase
B) reteplase recombinant
C) amylase
D) anistreplase

Question 21

Clotting is of the utmost importance in the protection of the body from undue ____________________.

Question 22

Thromboplastin and calcium react with prothrombin to create ____________________.

Question 23

Heparin is obtained from the liver and ____________________ of domestic animals.

Question 24

Warfarin is the mainstay of long-term ____________________ therapy.

Question 25

Warfarin is involved in the synthesis of prothrombin in the ____________________.

Question 26

The clumping together of platelets to form a clot is called __________.

Question 27

The process of blood clots is referred to as blood __________.

Question 28

Thrombolytics are drugs designed to __________ blood clots.

Question 29

Hemophilia is an inherited disorder in which the blood does not __________ properly.

Question 30

Deficiency of the clotting factor __________ may cause hemophilia.

Question 31

Heparin is found in the white blood cells known as __________.

Question 32

Spontaneous __________ is the major complication of heparin administration.

Question 33

__________ is the mainstay of long-term anticoagulant therapy.

Question 34

Sustained erection and __________ are the only two of the adverse effects of warfarin, but these are rare.

Question 35

The most commonly used antiplatelet drug is __________.

Question 36

Abciximab and ticlopidine are examples of __________ drugs.

Question 37

Clopidogrel is an antiplatelet agent used in patients who have recently had myocardial infarction or __________.

Question 38

An example of __________ is urokinase.

Question 39

Thrombolytic drugs, along with aspirin, may increase the risk of __________.

Question 40

A decrease in the number of platelets in blood circulation is called __________.

Question 41

Match the generic name with the trade name.

-urokinase

A) Eminase
B) Coumadin
C) Angiomax
D) Kabikinase
E) Abbokinase

Question 42

Match the generic name with the trade name.

-sterptokinase

A) Eminase
B) Coumadin
C) Angiomax
D) Kabikinase
E) Abbokinase

Question 43

Match the generic name with the trade name.

-anistreplase

A) Eminase
B) Coumadin
C) Angiomax
D) Kabikinase
E) Abbokinase

Question 44

Match the generic name with the trade name.

-warfarin

A) Eminase
B) Coumadin
C) Angiomax
D) Kabikinase
E) Abbokinase

Question 45

Match the generic name with the trade name.

-bivalirudin

A) Eminase
B) Coumadin
C) Angiomax
D) Kabikinase
E) Abbokinase

Question 46

Match the generic name with the trade name.

-urokinase

A)Streptase
B)Retavase
C)Eminase
D)Kinlytic
E)Activase

Question 47

Match the generic name with the trade name.

-alteplase

A)Streptase
B)Retavase
C)Eminase
D)Kinlytic
E)Activase

Question 48

Match the generic name with the trade name.

-reteplase

A)Streptase
B)Retavase
C)Eminase
D)Kinlytic
E)Activase

Question 49

Match the generic name with the trade name.

-anistreplase

A)Streptase
B)Retavase
C)Eminase
D)Kinlytic
E)Activase

Question 50

Match the generic name with the trade name.

-streptokinase

A)Streptase
B)Retavase
C)Eminase
D)Kinlytic
E)Activase