Question 1

A nurse provides teaching to a patient who will begin taking a drug with a known risk of hepatotoxicity. Which statement by the patient indicates a need for further teaching?&#10;A) &#34;I should avoid taking acetaminophen while taking this drug.&#34;&#10;B) &#34;I will need periodic evaluation of aspartate aminotransferase and alanine aminotransferase levels.&#34;&#10;C) &#34;If I experience nausea, vomiting, or abdominal pain, I should call my provider.&#34;&#10;D) &#34;Routine testing and early detection of problems will prevent liver failure.&#34;

Accepted Answer

Drug-induced liver injury can progress from undetectable to advanced between routine tests; therefore, routine testing does not always prevent liver failure. Patients taking known hepatotoxic drugs should avoid other drugs, such as acetaminophen, that can cause liver damage. Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are liver enzymes that are routinely monitored when a patient is taking hepatotoxic drugs. Nausea, vomiting, and abdominal pain are signs of liver injury and should be reported.

Question 2

Which actions occur in 90% of fatal medication errors?&#10;A) Confusing drugs with similar packaging&#10;B) Giving a drug intravenously instead of intramuscularly&#10;C) Giving Nasarel instead of Nizoral&#10;D) Using an infusion device that malfunctions&#10;E) Writing a prescription illegibly

Accepted Answer

Ninety percent of fatal medication errors fall into three categories: human factors, communication mistakes, and name confusion. Giving a drug IV (intravenously) instead of IM (intramuscularly) is an example of a human factor; writing a prescription so that it is illegible is an example of a communication mistake; and giving a drug with a name that sounds like the name of another drug is an example of name confusion. Confusion of drugs with similar packaging and using a faulty device also can cause fatal drug errors, but these factors do not fall into the categories that account for 90% of fatal errors.

Question 3

A patient is given a drug for the first time and develops shortness of breath. The patient's heart rate is 76 beats/min, the respiratory rate is 20 breaths per minute, and the blood pressure is 120/70 mm Hg. The nurse checks a drug administration manual to make sure the correct dose was given and learns that some patients taking the drug experience shortness of breath. The nurse will contact the provider to report what?

A) An allergic reaction
B) An idiosyncratic effect
C) An iatrogenic response
D) A side effect

A side effect

Accepted Answer

A side effect is a secondary drug effect produced at therapeutic doses. This patient received the correct dose of the drug and developed shortness of breath, which, in this case, is a drug side effect. To experience an allergic reaction, a patient must have prior exposure to a drug and sensitization of the immune response. An idiosyncratic effect results from a genetic predisposition to an uncommon drug response. An iatrogenic response occurs when a drug causes symptoms of a disease.

Question 4

Which patients are at increased risk for adverse drug events?&#10;A) A 2-month-old infant taking a medication for gastroesophageal reflux disease&#10;B) A 23-year-old female taking an antibiotic for the first time&#10;C) A 40-year-old male who is intubated in the intensive care unit and taking antibiotics and cardiac medications&#10;D) A 7-year-old female receiving insulin for diabetes&#10;E) An 80-year-old male taking medications for COPD

Accepted Answer

Patients at increased risk for adverse drug events include the very young, the very old, and those who have serious illnesses. Females, children, and young adults taking single medications do not have increased risks for adverse events.

Question 5

A patient is taking a drug that has known toxic side effects. What will the nurse do?&#10;A) Discontinue the drug at the first signs of toxicity.&#10;B) Ensure that complete blood counts are ordered periodically.&#10;C) Monitor the function of all organs potentially affected by the drug.&#10;D) Teach the patient how to treat the symptoms if they develop.

Accepted Answer

When a drug is administered that has known toxic side effects, the nurse is responsible for monitoring all organ systems potentially affected by the drug. Not all toxic side effects warrant discontinuation of the drug, and a nurse cannot discontinue a drug without an order from the provider. Complete blood counts are indicated only for drugs that affect the blood. Some drugs need to be discontinued, so teaching a patient to treat symptoms is not correct in all cases.

Question 6

A nursing student is preparing to give a medication that has a boxed warning. The student asks the nurse what this means. What will the nurse explain about boxed warnings?&#10;A) They indicate that a drug should not be given except in life-threatening circumstances.&#10;B) They provide detailed information about the adverse effects of the drug.&#10;C) They alert prescribers to measures to mitigate potential harm from side effects.&#10;D) They provide information about antidotes in the event that toxicity occurs.

Accepted Answer

Boxed warnings (also known as black box warnings) are used to alert providers to potential side effects and to ways to prevent or reduce harm from these side effects. A boxed warning is placed on any drug that, although useful, has serious side effects; this is a way to keep drugs on the market while protecting patients. Many of these drugs are used in situations that are not life threatening. The boxed warning provides a concise summary and not a detailed explanation of drug side effects. The boxed warning does not include antidotes to toxicity.

Question 7

A nurse is preparing to give an antibiotic to a patient who reports being allergic to antibiotics. Before giving the medication, what will the nurse do first?&#10;A) Ask whether the patient has taken this antibiotic for other infections.&#10;B) Question the patient about allergies to other medications.&#10;C) Request an order for a lower dose of the antibiotic.&#10;D) Request an order for an antihistamine.

Accepted Answer

The nurse needs to assess whether the patient is truly allergic to this drug. Allergic reactions require previous exposure to the drug, so the nurse should ask whether the patient has taken this antibiotic before. If a patient is allergic to a drug, lowering the dose will not decrease the risk of allergic reaction. Antihistamines sometimes are given when patients must take a drug to which they are allergic.

Question 8

A patient is being discharged after surgery. During the admission history, the nurse learned that the patient normally consumes 2 or 3 glasses of wine each day. The prescriber has ordered hydrocodone with acetaminophen [Lortab] for pain. What will the nurse do?

A) Request an order for acetaminophen without hydrocodone for pain.
B) Suggest that the patient use ibuprofen for pain.
C) Tell the patient not to drink wine while taking Lortab.
D) Tell the patient to limit wine intake to 1 or 2 glasses per day.

Accepted Answer

Combining a hepatotoxic drug with certain other drugs may increase the risk of hepatotoxicity. When even therapeutic doses of acetaminophen are taken with alcohol, the acetaminophen can cause liver damage. Patients should be cautioned not to drink alcohol; even 2 drinks with acetaminophen can produce this effect. Hydrocodone does not contribute to hepatotoxicity. Ibuprofen is not indicated for postoperative pain unless the pain is mild. Limiting wine to 1 or 2 glasses per day still increases the risk of hepatotoxicity.

Question 9

A patient is taking sertraline [Zoloft] for depression, and the provider orders azithromycin [Zithromax] to treat an infection. What will the nurse do?&#10;A) Contact the provider to discuss an alternative to azithromycin.&#10;B) Request an order for a different antidepressant medication.&#10;C) Request an order to reduce the dose of sertraline.&#10;D) Withhold the sertraline while giving the azithromycin.

Accepted Answer

Both sertraline and azithromycin prolong the QT interval, and when taken together, they increase the risk of fatal dysrhythmias. Because the antibiotic is used for a short time, it is correct to consider using a different antibiotic. Reducing the dose of sertraline does not alter the combined effects of two drugs that lengthen the QT interval. Sertraline should not be stopped abruptly, so withholding it during antibiotic therapy is not indicated.

Question 10

A nurse is preparing to administer a drug. Upon reading the medication guide, the nurse notes that the drug has been linked to symptoms of Parkinson disease in some patients. What will the nurse do?&#10;A) Ask the patient to report these symptoms, which are known to be teratogenic effects.&#10;B) Observe the patient closely for such symptoms and prepare to treat them if needed.&#10;C) Request an order to evaluate the patient's genetic predisposition to this effect.&#10;D) Warn the patient about these effects and provide reassurance that this is expected.

Accepted Answer

A drug that causes disease-like symptoms is known to be iatrogenic. Nurses should be prepared for this possibility and be prepared to withdraw the drug if necessary and treat the symptoms. Such effects are not teratogenic. Patients with a genetic predisposition to respond differently to drugs are known to have idiosyncratic effects. Iatrogenic effects, even when known, are not typically expected side effects.

Question 11

A patient is given a new medication and reports nausea within an hour after taking the drug. The nurse consults the drug information manual and learns that nausea is not an expected adverse effect of this drug. When the next dose is due, what will the nurse do?

A) Administer the drug and tell the patient to report further nausea.
B) Hold the drug and notify the provider of the patient's symptoms.
C) Report the symptoms of nausea to the MEDWATCH program.
D) Request an order for an antiemetic to counter this drug's effects.

Accepted Answer

The answer of A patient is given a new medication...

Question 12

Which are effective ways to help prevent medication errors?&#10;A) Developing nonpunitive approaches to track errors&#10;B) Focusing on caregivers who make errors&#10;C) Helping patients to be active, informed members of the healthcare team&#10;D) Naming, blaming, and shaming those who make errors&#10;E) Using electronic medical order entry systems

Accepted Answer

The answer of Which are effective ways to help prevent...

Question 13

A nurse is reviewing a medication administration record before administering medications. Which order will the nurse implement?&#10;A) Furosemide [Lasix] 20 mg QD PO&#10;B) Furosemide [Lasix] 20 mg qd PO&#10;C) Furosemide [Lasix] 20 mg daily&#10;D) Furosemide [Lasix] 20 mg PO daily

Accepted Answer

The answer of A nurse is reviewing a medication administration...

Deck 7: Adverse Drug Reactions and Medication Errors