Deck 46: Antineoplastic Drugs Part 2: Cell Cyclenonspecific Drugs and Miscellaneous Drugs

Question 1

During therapy with the cytotoxic antibiotic bleomycin, the nurse will assess for a potentially serious adverse effect by monitoring which assessment finding?

A) Blood urea nitrogen and creatinine levels
B) Cardiac ejection fraction
C) Respiratory function
D) Peripheral nerve sensation

Answer 1

Respiratory function

Question 2

What is the nurse's priority action if extravasation of an antineoplastic drug occurs during intravenous (IV) administration?

A) Reduce the infusion rate.
B) Discontinue the IV, and apply warm compresses.
C) Stop the infusion immediately, but leave the IV catheter in place.
D) Change the infusion to normal saline, and inject the area with hydrocortisone.

Answer 2

Stop the infusion immediately, but leave the IV catheter in place.

Question 3

The nurse is teaching a class about the various chemotherapy drugs and explains that alkylating drugs are also called "cell cycle-nonspecific drugs" because they are

A) cytotoxic during a specific cell cycle.
B) cytotoxic in any phase of the cell cycle.
C) effective against several types of neoplasms.
D) more highly differentiated than cell cycle-specific drugs.

Answer 3

cytotoxic in any phase of the cell cycle.

Question 4

A female patient is receiving palliative therapy with androgen hormones as part of treatment for inoperable breast cancer. The nurse will discuss with the patient which potential body image changes that may occur as adverse effects?

A) Hirsutism and acne
B) Weight gain
C) Flushing and hot flashes
D) Alopecia and body odor

Question 5

A patient is receiving doxorubicin (Adriamycin) as part of treatment for ovarian cancer. Which nursing diagnosis is related to this antineoplastic drug?

A) Decreased cardiac output related to the adverse effect of cardiotoxicity
B) Ineffective breathing pattern related to the adverse effect of pulmonary toxicity
C) Risk for injury related to the effects of neurotoxicity (ataxia, numbness of hands and feet)
D) Impaired urinary elimination pattern related to hyperuricemia

Question 6

During chemotherapy, a patient develops severe diarrhea caused by a vasoactive intestinal peptide-secreting tumor ( VIPoma ). The nurse expects to administer which drug for this problem?

A) dexrazoxane ( Zinecard )
B) allopurinol ( Zyloprim )
C) octreotide ( Sandostatin )
D) bismuth subsalicylate ( Pepto-Bismol )

Question 7

When a patient is receiving cisplatin (Platinol-AQ) chemotherapy, the nurse will monitor for which adverse effects? (Select all that apply.)

A) Tinnitus
B) Heart failure
C) Hearing loss
D) Elevated blood urea nitrogen and creatinine levels
E) Numbness or tingling in the extremities
F) Elevated glucose and ketone levels

Question 8

A patient is receiving a third session of chemotherapy with daunorubicin (Cerubidine). The nurse will assess the patient for which signs of a potential severe toxic effect of this drug?

A) Tinnitus and hearing loss
B) Numbness and tingling in the fingers
C) A weight gain of 2 pounds or more in 24 hours
D) Decreased blood urea nitrogen and creatinine levels

Question 9

A patient will be receiving mitoxantrone (Novantrone), 12 mg/m² every 3 weeks, as part of treatment for prostate cancer. Each dose is mixed into a 50-mL bag of D₅W and needs to infuse over 15 minutes. The infusion pump delivers the dose at mL/hour. The nurse will set the pump to infuse at what rate?

Question 10

Just before the second course of chemotherapy, the laboratory calls to report that the patient's neutrophil count is 450 cells/mm³. The nurse expects that the oncologist will follow which course of treatment?

A) Chemotherapy will continue as scheduled.
B) Chemotherapy will resume with a lowered dosage.
C) Chemotherapy will resume after a transfusion of neutrophils.
D) Chemotherapy will be withheld until the neutrophil count returns toward normal levels.

Question 11

When hanging a new infusion bag of a chemotherapy drug, the nurse accidentally spills a small amount of the solution onto the floor. Which action by the nurse is appropriate?

A) Let it dry, and then mop the floor.
B) Wipe the area with a disposable paper towel.
C) Use a spill kit to clean the area.
D) Ask the housekeeping department to clean the floor.

Question 12

When giving cisplatin (Platinol-AQ), the nurse is aware that the major dose-limiting effect of this drug is which condition?

A) Alopecia
B) Kidney damage
C) Cardiotoxicity
D) Stomatitis

Question 13

The nurse is assessing a patient who is receiving chemotherapy with an alkylating drug. Which assessment findings would be considered indications of an oncologic emergency? (Select all that apply.)

A) Dry, "scratchy," or "swollen" throat
B) Loss of hair
C) Decreased red blood cell count
D) White patches in the mouth or throat
E) Temperature of 100.7° F ( 38.2° C )
F) Decreased urine output