Deck 42: Antifungal Drugs

Question 1

Which of the following drugs may be used for invasive aspergillosis in patients who cannot tolerate other antifungal drugs?

A)fluconazole (Diflucan)
B)flucytosine (5-FC)
C)caspofungin (Cancidas)
D)nystatin (Dom-Nystatin)

Answer 1

caspofungin (Cancidas)

Question 2

The nurse is reviewing the history of a patient who will be taking an antifungal drug.Which of the following conditions is a contraindication for this treatment therapy?

A)Diabetes mellitus
B)Renal failure
C)Hyperthyroidism
D)Meningitis

Answer 2

Renal failure

Question 3

During administration of amphotericin B (Fungizone),the patient may experience severe adverse effects,such as fever,chills,hypotension,tachycardia,malaise,nausea,and headache.Which of the following is the correct action for the nurse to take?

A)Discontinuing the infusion immediately
B)Reducing the infusion rate gradually until the adverse effects subside
C)Administering the medication by rapid intravenous (IV) infusion to reduce the potential adverse effects
D)Anticipating these effects and pretreating with an antipyretic,such as acetaminophen,an antihistamine,and an antiemetic drug

Answer 3

Anticipating these effects and pretreating with an antipyretic,such as acetaminophen,an antihistamine,and an antiemetic drug

Question 4

The nurse is administering one of the newer formulations of amphotericin B,Amphotec.When giving this drug,what important information does the nurse need to remember?

A)The new formulation may be given in an oral form.
B)The newer doses are much lower than the older doses.
C)The newer doses are much higher than the older doses.
D)The newer and older forms have no differences in their doses.

Question 5

A patient has been prescribed ketoconazole.What important instructions should the nurse tell the patient about this drug?

A)Have your liver function tested.
B)Take antacids with the drug to minimize gastrointestinal upset.
C)Take the drug with a large glass of orange juice or water.
D)Take the drug 2 hours before a meal or 2 hours after a meal.

Question 6

The nurse is administering an antifungal medication.What assessment finding may indicate medication-induced renal damage?

A)Rash and chills
B)Increased urinary output
C)Decreased levels of blood urea nitrogen (BUN) and creatinine
D)Weight gain of more than 1 kg in 1 week

Question 7

Which of the following are contraindications to the use of griseofulvin?

A)Lupus
B)Renal disease
C)Cardiac disease
D)Meningitis

Question 8

A patient has been prescribed a vaginal antifungal drug.What important information should the nurse teach the patient about this drug?

A)Continue the medication until the treatment is completed even if symptoms are relieved earlier.
B)Discontinue this medication if menstruation begins.
C)Daily douching is part of the treatment for vaginal fungal infections.
D)Avoid consumption of alcohol.

Question 9

A patient is receiving therapy with amphotericin B (Fungizone).The nurse will monitor for known adverse effects that are reflected by which laboratory result?

A)Serum potassium level of 2.9 mmol/L
B)Serum potassium level of 5.6 mmol/L
C)White blood cell (WBC) count of 6500 mm3
D)Platelet count of 300,000 per microlitre

Question 10

A patient with a severe fungal infection has been ordered voriconazole (Vfend).Which of the following assessment findings should the nurse be concerned about before the medication is started?

A)Decreased breath sounds in the lower lobes
B)History of cardiac dysrhythmias
C)History of type 2 diabetes
D)Potassium level of 3.8 mmol/L

Question 11

Which antifungal drug causes decreased effects of oral anticoagulants?

A)miconazole
B)griseofulvin
C)ketoconazole
D)amphotericin B (Fungizone)

Question 12

The nurse is administering amphotericin B (Fungizone).Which of the following actions by the nurse are appropriate? Select all that apply.

A)Administering the medication by rapid intravenous (IV)infusion
B)Discontinuing the drug immediately if the patient develops tingling and numbness in the extremities
C)If adverse effects occur, reducing the IV rate gradually until the adverse effects subside
D)Using an infusion pump with intravenous therapy
E)Monitoring the IV site for signs of phlebitis and infiltration
F)Ordering premedication for fever and nausea
G)Ensuring that the intravenous solution for amphotericin B is cloudy
H)Monitoring for muscle twitching,which may indicate hypokalemia