Deck 14: Blood Component Preparation and Therapy
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Deck 14: Blood Component Preparation and Therapy
1
Rejuvenation of a unit of RBCs is a method used to:
A)inactivate viruses.
B)restore 2,3 DPG and ATP levels.
C)increase the expiration date by 21 days.
D)prepare a unit for freezing in high glycerol.
A)inactivate viruses.
B)restore 2,3 DPG and ATP levels.
C)increase the expiration date by 21 days.
D)prepare a unit for freezing in high glycerol.
B
Additives in rejuvenation solutions increase the 2,3 DPG and ATP levels of an expired unit,allowing for freezing within 3 days.
Additives in rejuvenation solutions increase the 2,3 DPG and ATP levels of an expired unit,allowing for freezing within 3 days.
2
To prevent graft-versus-host disease,blood components prepared for a fetus that needs an intrauterine transfusion should be:
A)saline washed.
B)irradiated.
C)frozen and deglycerolized.
D)human leukocyte antigen-matched.
A)saline washed.
B)irradiated.
C)frozen and deglycerolized.
D)human leukocyte antigen-matched.
B
Irradiation prevents the leukocytes from dividing and causing a graft-versus-host reaction.
Irradiation prevents the leukocytes from dividing and causing a graft-versus-host reaction.
3
The temperature of a shipment of red blood cell units that was received from the local blood center was recorded as 8° C.The correct course of action is to:
A)place the units in inventory because the temperature is acceptable.
B)quarantine the units until approved by the supervisor.
C)send the units back to the blood center.
D)have the units tested for bacterial contamination before release.
A)place the units in inventory because the temperature is acceptable.
B)quarantine the units until approved by the supervisor.
C)send the units back to the blood center.
D)have the units tested for bacterial contamination before release.
A
Shipment of red blood cells should be between 1° and 10° C,and the units are acceptable to use.
Shipment of red blood cells should be between 1° and 10° C,and the units are acceptable to use.
4
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
AS-3 or AS-2
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
AS-3 or AS-2
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5
Addition of which of the following will increase the shelf life of red blood cells?
A)Heparin
B)AS-3
C)Lactated Ringer's
D)Citrate
A)Heparin
B)AS-3
C)Lactated Ringer's
D)Citrate
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6
The maximum acceptable storage temperature for frozen red blood cells is:
A)4° C.
B)-12° C.
C)-20° C.
D)-65° C.
A)4° C.
B)-12° C.
C)-20° C.
D)-65° C.
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7
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
Frozen
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
Frozen
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8
Leukocyte-reduced red blood cells are indicated for patients with:
A)febrile transfusion reactions.
B)iron deficiency anemia.
C)hemophilia A.
D)cancer undergoing chemotherapy treatments.
A)febrile transfusion reactions.
B)iron deficiency anemia.
C)hemophilia A.
D)cancer undergoing chemotherapy treatments.
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9
Plasma,frozen within 24 hours of collection (PF24),has similar coagulation factors as:
A)FFP.
B)CRYO.
C)thawed plasma.
D)recovered plasma.
A)FFP.
B)CRYO.
C)thawed plasma.
D)recovered plasma.
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10
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
Irradiated
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
Irradiated
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11
Whole blood collected from a donor should remain at what temperature before the separation and preparation of platelet concentrates?
A)20° to 24° C
B)1° to 6° C
C)1° to 10° C
D)Varies with the facility
A)20° to 24° C
B)1° to 6° C
C)1° to 10° C
D)Varies with the facility
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12
An important determination of platelet viability following the recommended storage interval is the:
A)platelet count.
B)pH.
C)PTT.
D)oxygen level.
A)platelet count.
B)pH.
C)PTT.
D)oxygen level.
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13
The correct storage temperature and time limit for pooled platelets are:
A)20° to 24° C,5 days.
B)1° to 6° C,7 days.
C)1° to 10° C,24 hours.
D)20° to 24° C,4 hours.
A)20° to 24° C,5 days.
B)1° to 6° C,7 days.
C)1° to 10° C,24 hours.
D)20° to 24° C,4 hours.
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14
A unit of CPDA-1 RBCs,expiring in 35 days,is split using a sterile collection device to prepare pediatric units.Each unit can be relabeled with an expiration date as:
A)4 days from collection.
B)4 days from sterile docking.
C)35 days from collection.
D)28 days from collection.
A)4 days from collection.
B)4 days from sterile docking.
C)35 days from collection.
D)28 days from collection.
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15
Once the cryoprecipitate has been removed from fresh frozen plasma,the remaining plasma can be refrozen and stored at -18° C for 1 year from collection.This product is useful for which of the following conditions?
A)Thrombotic thrombocytopenic purpura
B)Hemophilia
C)Warfarin overdose
D)Volume replacement following surgery
A)Thrombotic thrombocytopenic purpura
B)Hemophilia
C)Warfarin overdose
D)Volume replacement following surgery
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16
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
CPD
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
CPD
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17
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
CPDA-1
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
CPDA-1
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18
Plastic overwraps are recommended for thawing FFP and CRYO to prevent:
A)contamination of the water bath.
B)rapid thawing,which affects labile factors.
C)entry ports from being contaminated with water.
D)the label from peeling off when thawing.
A)contamination of the water bath.
B)rapid thawing,which affects labile factors.
C)entry ports from being contaminated with water.
D)the label from peeling off when thawing.
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19
Following a platelet concentrate transfusion,a patient did not obtain the calculated corrected count increment that was expected.The possible reason(s)this did not occur is (are)the:
A)patient had a fever.
B)patient was actively bleeding.
C)patient has leukocyte antibodies.
D)All of the above are correct.
A)patient had a fever.
B)patient was actively bleeding.
C)patient has leukocyte antibodies.
D)All of the above are correct.
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20
Platelet concentrates that are prepared from whole blood have a minimum quality control limit of __________ platelets in __________ of the units tested.
A)3 * 1011,75%
B)1 * 1010,75%
C)5.5*1010,all
D)5.5 * 1010,75%
A)3 * 1011,75%
B)1 * 1010,75%
C)5.5*1010,all
D)5.5 * 1010,75%
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21
Match the blood component with the correct storage and expiration limit.Each choice may be used more than once or not at all.a.20° to 24° C,4 hours
b.1° to 6° C,24 hours
c.20° to 24° C,6 hours
d.< -18° C,1 year from collection
e.1° to 6° C,< 5 days
f.< -65° C,7 years
g.20° to 24° C,48 hours
Cryoprecipitated AHF (thawed)
b.1° to 6° C,24 hours
c.20° to 24° C,6 hours
d.< -18° C,1 year from collection
e.1° to 6° C,< 5 days
f.< -65° C,7 years
g.20° to 24° C,48 hours
Cryoprecipitated AHF (thawed)
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22
Match the blood component with the correct storage and expiration limit.Each choice may be used more than once or not at all.a.20° to 24° C,4 hours
b.1° to 6° C,24 hours
c.20° to 24° C,6 hours
d.< -18° C,1 year from collection
e.1° to 6° C,< 5 days
f.< -65° C,7 years
g.20° to 24° C,48 hours
Liquid plasma from whole blood
b.1° to 6° C,24 hours
c.20° to 24° C,6 hours
d.< -18° C,1 year from collection
e.1° to 6° C,< 5 days
f.< -65° C,7 years
g.20° to 24° C,48 hours
Liquid plasma from whole blood
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23
Match the blood component with the correct storage and expiration limit.Each choice may be used more than once or not at all.a.20° to 24° C,4 hours
b.1° to 6° C,24 hours
c.20° to 24° C,6 hours
d.< -18° C,1 year from collection
e.1° to 6° C,< 5 days
f.< -65° C,7 years
g.20° to 24° C,48 hours
Cryoprecipitated AHF,pooled
b.1° to 6° C,24 hours
c.20° to 24° C,6 hours
d.< -18° C,1 year from collection
e.1° to 6° C,< 5 days
f.< -65° C,7 years
g.20° to 24° C,48 hours
Cryoprecipitated AHF,pooled
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24
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
Leukoreduced (AS-3)
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
Leukoreduced (AS-3)
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25
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
Deglycerolized
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
Deglycerolized
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26
Match the blood component with the correct storage and expiration limit.Each choice may be used more than once or not at all.a.20° to 24° C,4 hours
b.1° to 6° C,24 hours
c.20° to 24° C,6 hours
d.< -18° C,1 year from collection
e.1° to 6° C,< 5 days
f.< -65° C,7 years
g.20° to 24° C,48 hours
Fresh frozen plasma (thawed)
b.1° to 6° C,24 hours
c.20° to 24° C,6 hours
d.< -18° C,1 year from collection
e.1° to 6° C,< 5 days
f.< -65° C,7 years
g.20° to 24° C,48 hours
Fresh frozen plasma (thawed)
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27
Match the blood component with the correct storage and expiration limit.Each choice may be used more than once or not at all.a.20° to 24° C,4 hours
b.1° to 6° C,24 hours
c.20° to 24° C,6 hours
d.< -18° C,1 year from collection
e.1° to 6° C,< 5 days
f.< -65° C,7 years
g.20° to 24° C,48 hours
Plasma,cryoprecipitate reduced,thawed
b.1° to 6° C,24 hours
c.20° to 24° C,6 hours
d.< -18° C,1 year from collection
e.1° to 6° C,< 5 days
f.< -65° C,7 years
g.20° to 24° C,48 hours
Plasma,cryoprecipitate reduced,thawed
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28
Match the correct expiration limit with each red blood cell product.Each choice may be used more than once or not at all.a.21 days
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
Pheresis (ACD)
b.35 days
c.42 days
d.10 years
e.28 days
f.24 hours
g.48 hours
h.72 hours
Pheresis (ACD)
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29
Match the blood component with the correct storage and expiration limit.Each choice may be used more than once or not at all.a.20° to 24° C,4 hours
b.1° to 6° C,24 hours
c.20° to 24° C,6 hours
d.< -18° C,1 year from collection
e.1° to 6° C,< 5 days
f.< -65° C,7 years
g.20° to 24° C,48 hours
Cryoprecipitated AHF (frozen)
b.1° to 6° C,24 hours
c.20° to 24° C,6 hours
d.< -18° C,1 year from collection
e.1° to 6° C,< 5 days
f.< -65° C,7 years
g.20° to 24° C,48 hours
Cryoprecipitated AHF (frozen)
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