Deck 12: Nonsteroidal Antiasthma Agents

Question 1

Zafirlukast is a

A)leukotriene receptor stimulator.
B)leukotriene receptor antagonist.
C)β adrenergic.
D)corticosteroid.

Answer 1

leukotriene receptor antagonist.

Question 2

Singulair can be administered to which of the following patient populations?
1)Adults and adolescents 15 years or older
2)Pediatric patients 6 to 14 years
3)Pediatric patients 2 to 5 years
4)Pediatric patients 12 to 23 months
5)Pediatric patients 6 to 23 months

A)1 and 2 only
B)1 only
C)1,2,and 3 only
D)1,2,3,4,and 5

Answer 2

1,2,3,4,and 5

Question 3

Mast cells are

A)chemical mediators that cause inflammation.
B)agents that block the inflammatory response in asthma.
C)agents used prophylactically to treat the inflammatory response in asthma.
D)connective tissue cells that contain heparin and histamine.

Answer 3

connective tissue cells that contain heparin and histamine.

Question 4

Zileuton interacts with which of the following respiratory care drugs?
1)Theophylline
2)Albuterol
3)Warfarin
4)Ipratropium bromide
5)Beclomethasone

A)1 and 3 only
B)2 and 4 only
C)3 and 5 only
D)1 and 5 only

Question 5

Leukotrienes exhibit which of the following effects?
1)Increased mucus secretion
2)Inhibition of normal ciliary action
3)Increased airway edema
4)Bronchoconstriction
5)Recruitment of other inflammatory cells into airways

A)4 only
B)1,2,and 4 only
C)3,4,and 5 only
D)1,2,3,4,and 5

Question 6

What is the clinical indication for use of antileukotriene drug therapy,such as montelukast,in asthma?

A)As a rescue bronchodilator in step 1 asthma
B)As a long-acting bronchodilator in step 3 asthma
C)As an alternative to inhaled steroids
D)As a mast cell stabilizer

Question 7

Cromolyn sodium is effective in preventing bronchospasm by

A)inhibiting mast cell degranulation.
B)blocking cholinergic receptor sites.
C)enhancing mast cell degranulation.
D)stimulating 2-adrenergic sites.

Question 8

Which of the following are antileukotriene agents?
1)Zafirlukast
2)Zileuton
3)Cromolyn sodium
4)Montelukast

A)1,2,and 4 only
B)3 and 4 only
C)1,2,and 3 only
D)2,3,and 4 only

Question 9

The general indication for clinical use of nonsteroidal antiasthma agents is

A)short-term control of bronchospasm.
B)prophylactic management of mild persistent asthma.
C)long-term control of bronchospasm.
D)control of severe asthma attack.

Question 10

After a patient begins using cromolyn sodium,how long may it take before clinical improvement in the patient's symptoms is seen?

A)24 hours
B)4 to 6 days
C)2 to 4 weeks
D)1 to 3 months

Question 11

The only antileukotriene agent currently approved for use in patients younger than 5 years of age is

A)zafirlukast.
B)Singulair.
C)Accolate.
D)Xolair.

Question 12

The usual dose of nebulized cromolyn sodium is

A)10 mg four times per day.
B)20 mg four times per day.
C)30 mg three times per day.
D)80 mg three times per day.

Question 13

Nonsteroidal antiasthma drugs are

A)relievers.
B) ( antagonists.)
C)antiinfectives.
D)controllers.

Question 14

Cromolyn sodium is available in what form?

A)Nebulizer solution
B)Tablet
C)MDI
D)Nasal spray

Question 15

Accolate is the brand name for which medication?

A)Zafirlukast
B)Montelukast
C)Zileuton
D)Omalizumab

Question 16

Which of the following nonsteroidal antiasthma agents is formulated as a subcutaneous injection?

A)Zileuton
B)Xolair
C)Montelukast
D)Zafirlukast

Question 17

Which of the following agents is considered a mast cell stabilizer?

A)Montelukast
B)Zafirlukast
C)Cromolyn sodium
D)Zileuton

Question 18

Which type of asthma is associated with allergic reactions?

A)Chronic
B)Intrinsic
C)Acute
D)Extrinsic

Question 19

Zileuton is administered by

A)DPI.
B)tablet.
C)MDI.
D)nebulizer.

Question 20

The most commonly reported side effect of cromolyn sodium is

A)diarrhea.
B)pneumonia.
C)nasal congestion.
D)headache.

Question 21

A 22-year-old patient is experiencing an acute exacerbation of her asthma and is complaining of wheezing and shortness of breath.Which is the most appropriate medication to help relieve her symptoms?

A)Omalizumab
B)Zileuton
C)Cromolyn sodium
D)Albuterol

Question 22

Which of the following is an advantage to the use of antileukotriene agents?

A)Multiple ways of administration
B)No interaction with inhaled steroids
C)Effective in more than 90% of patients
D)All formulations are available for pediatric use

Question 23

What is the mechanism of action for Singulair?

A)5-LO inhibitor
B)Leukotriene receptor antagonist
C)Leukotriene receptor agonist
D)Monoclonal antibodies

Question 24

Bobby is in a sickle cell crisis.Along with his pain medications,he received a medication via inhalation.His mother asks you if you know what the medication was.What is one possibility?

A)Albuterol
B)Cromolyn
C)Combivent
D)Relenza

Question 25

Allergic inflammation of the airway is the product of an immune response,and the ________________ plays a central role in attracting mast cells and eosinophils.

A)T lymphocyte
B)B lymphocyte
C)A and B
D)Neither A nor B

Question 26

Zach is a 14 year old with complaints of shortness of breath and wheezing when working out.He currently takes albuterol and theophylline.What medication may help with his symptoms?

A)Xolair
B)Cromolyn
C)Singulair
D)Accolate

Question 27

Which of the following is a monoclonal antibody used to treat asthma?

A)Omalizumab
B)Zileuton
C)Zafirlukast
D)Montelukast