Deck 16: Selected Agents of Pulmonary Value

Question 1

The drug used to treat hypoxic respiratory failure in newborns with pulmonary hypertension is

A)ribavirin.
B)Xopenex.
C)Survanta.
D)nitric oxide.

Answer 1

nitric oxide.

Question 2

Nitric oxide (NO)should not be used in neonates with

A)left-to-right shunts.
B)pulmonary hypertension.
C)right-to-left shunts.
D)increased pulmonary artery pressure.

Answer 2

right-to-left shunts.

Question 3

Prolastin is

A)a corticosteroid.
B)an antihistamine.
C)an $\alpha$ -proteinase inhibitor.
D)a bronchodilator.

Answer 3

an $\alpha$ -proteinase inhibitor.

Question 4

Smoking cessation drugs are available in which of the following forms?
1)Gum
2)Nasal spray
3)Transdermal patch
4)Intravenous infusion
5)Tablets

A)1 and 3 only
B)2,3,and 5 only
C)1,2,3,and 5 only
D)1,2,3,4,and 5

Question 5

An 80-kg man should receive what dose of Prolastin?

A)2400 mg weekly
B)480 mg daily
C)4800 mg weekly
D)240 mg daily

Question 6

The major limitation of Prolastin therapy is

A)lack of availability.
B)cost.
C)no FDA approval.
D)severe adverse effects.

Question 7

Physical symptoms of nicotine withdrawal include which of the following?
1)Irritability
2)Weight gain
3)Craving for nicotine
4)Anxiety
5)Sleep disturbances

A)3 only
B)1,2,and 4 only
C)2,3,and 5 only
D)1,2,3,4,and 5

Question 8

The nicotine replacement method that provides the most consistent level of nicotine and that is easy and convenient is

A)the transdermal patch.
B)gum.
C)a nasal spray.
D)an inhaler.

Question 9

Nicotine replacement agents are indicated to

A)simulate the act of smoking.
B)relieve nicotine withdrawal symptoms.
C)punish negative behaviors.
D)produce strong adverse effects of smoking.

Question 10

___________ is not used pharmacologically to treat smoking addiction.

A)Nicotine replacement patch
B)Varenicline (Chantix)
C)Bupropion (Zyban)
D)Prolastin

Question 11

Potential adverse effects of Prolastin administration include which of the following?
1)Hypertension
2)Fever
3)Arrhythmias
4)Exacerbation
5)Flulike symptoms

A)1 and 3 only
B)2,4,and 5 only
C)1,2,and 4 only
D)1,2,3,4,and 5

Question 12

Which of the following is the enzyme that is responsible for cleaving good lung tissue in $\alpha$ ₁-antitrypsin deficiency?

A)Prolastin
B)Neutrophil elastase
C)Leukocyte protease inhibitor
D)Zemaira

Question 13

The recommended dosage of Prolastin is

A)30 mg/kg once daily.
B)40 mg/kg once weekly.
C)50 mg/kg once weekly.
D)60 mg/kg once weekly.

Question 14

Nitric oxide (NO)is a

A)cardiac stimulant.
B)pulmonary vasodilator.
C)pulmonary vasoconstrictor.
D)systemic vasodilator.

Question 15

The recommended dose of nitric oxide (NO)is

A)20 ppm.
B)30 ppm.
C)40 ppm.
D)60 ppm.

Question 16

Bupropion is an

A)anxiolytic.
B)antidepressant.
C)anticholinergic.
D)antibiotic.

Question 17

Emphysema is a process of

A)excessive mucus secretion.
B)large airway dilation.
C)bronchial smooth muscle constriction.
D)alveolar wall destruction.

Question 18

Zyban is a(n)

A)nicotine replacement.
B)bronchodilator.
C)antidepressant.
D)steroid.

Question 19

A drug intended for therapy of congenital $\alpha$ ₁-antitrypsin deficiency is

A)pulmozyme.
B)pneumovax.
C)prolastin.
D)prednisone.

Question 20

The physician suspects that your patient may have $\alpha$ ₁-antitrypsin ( $\alpha$ -AT)deficiency.Which disease process would help to confirm this diagnosis?

A)Panacinar emphysema
B)Centrilobular emphysema
C)Bronchiectasis
D)Asthma

Question 21

Signs of strong physical addiction to nicotine include
1)inhaling smoke frequently and deeply.
2)smokes even when ill enough to be bed-ridden.
3)can smoke less than 10 cigarettes a day if in a smoke-free environment.
4)smokes within 30 minutes of waking up.

A)1 and 2 only
B)2 and 3 only
C)1,2,and 4 only
D)1,2,3,and 4

Question 22

Individuals attempting to quit smoking using Nicotrol should be advised

A)If taken while using tobacco products,potential toxic concentrations of nicotine can occur in the blood.
B)Bupropion has a better quit rate compared with Chantix.
C)The treatment process lasts 3 weeks.
D)Nortriptyline is another smoking cessation option approved by the FDA for individuals who fail to quit smoking with Chantix.

Question 23

A smoker with very low dependency seeks your advice about smoking cessation.What nicotine replacement agent would you suggest?

A)Nicotine replacement patch (21 mg)
B)Varenicline (Chantix)
C)Nicotine inhaler
D)Bupropion

Question 24

Respiratory care assessment of smoking cessation drug therapy includes
1)monitoring abstinence rates at intervals such as 3,6,or 12 months.
2)monitoring for symptoms of nicotine overdose.
3)counseling and support throughout treatment for smoking cessation.
4)assessing patients for weight gain and encouraging an exercise program.

A)1 and 2 only
B)2 and 3 only
C)1,2,and 3 only
D)1,2,3,and 4

Question 25

Ventavis is indicated for
1)pulmonary arterial hypertension.
2)type 1 diabetes mellitus.
3)type 2 diabetes mellitus.
4) $\alpha$ ₁-antitrypsin deficiency.
5)smoking cessation.

A)1 only
B)2,3,and 5 only
C)2 and 3 only
D)4 only

Question 26

The two inhaled prostacyclin analogues available in the United States are

A)Iloprost and Tyvaso.
B)Varenicline and bupropion.
C)Albuterol and Atrovent.
D)Xopenex and Survanta.

Question 27

Toxic products of nitric oxide (NO)include
1)nitrogen dioxide.
2)formation of methemoglobin.
3)type 2 diabetes mellitus.
4) $\alpha$ ₁-antitrypsin deficiency.

A)1 and 2 only
B)2 and 3 Only
C)2 and 3 only
D)4 only