Deck 65: Viruses in Human Disease

Question 1

MATCHING
Match the Flavivirus with its characteristics.
a.Yellow fever
b.Dengue fever
c.West Nile virus
d.Hepatitis C
Black vomit

Answer 1

A

Question 2

A 36-year-old woman is on a cruise ship and later develops nausea, abdominal pain, vomiting, and diarrhea.She is most likely suffering from which virus?

A) Norovirus
B) Rotavirus
C) Coronavirus
D) Torovirus

Answer 2

A
Norovirus is the source for more than 80% of nonbacterial acute gastroenteritis and more than 50% of foodborne outbreaks for all ages in developed and underdeveloped countries.Of major public health concern is its ability to cause large outbreaks in semiclosed environments.In recent years, noroviruses have been implicated in large outbreaks of disease on cruise ships and in nursing homes, schools, summer camps, hospitals, and restaurants.

Question 3

Lymphocytic choriomeningitis (LCM)and Lassa fever are considered which type of virus?

A) Adenovirus
B) Papillomavirus
C) Picornavirus
D) Arenavirus

Answer 3

D
LCM and Lassa fever (Lassa, Nigeria)are arenaviruses.

Question 4

Which cell line has demonstrated a consistent season-to-season isolation frequency of influenza viruses?

A) Primary monkey kidney
B) Lung fibroblasts
C) HeLa
D) HEp-2

Question 5

Which of the following patterns of markers is a normal immune response after recovery from a hepatitis B viral (HBV)infection?

A) Negative hepatitis B surface antigen (HBsAg); negative hepatitis B core antibody (anti-HBcAb); and negative hepatitis B surface antibody (anti-HBsAb)
B) Positive HBsAg; negative anti-HBcAb; and negative anti-HBsAb
C) Positive HBsAg; positive HBeAg (hepatitis B e antigen); and negative anti-HBsAb
D) Negative HBsAg; positive anti-HBcAb; and positive anti-HBsAb

Question 6

MATCHING
Match the Flavivirus with its characteristics.
a.Yellow fever
b.Dengue fever
c.West Nile virus
d.Hepatitis C
Carcinoma

Question 7

A 37-year-old man traveling through South America has a sudden onset of fever, severe headache, and chills.A macropapular rash develops on his trunk, which then spreads to his face and extremities.The vector transmitting this disease is most likely:

A) ticks.
B) mosquitos.
C) lice.
D) sandflies.

Question 8

An 8-month-old female infant is admitted to the emergency department in respiratory distress on Christmas Eve.A nasopharyngeal aspirate is obtained and sent to the laboratory on ice for analysis.The most probable organism that would be isolated is:

A) varicella zoster virus.
B) respiratory syncytial virus (RSV).
C) rotavirus.
D) coxsackievirus.

Question 9

Severe acute respiratory syndrome (SARS)has what characteristic structures when visualized under an electron microscope?

A) Glycoprotein spikes
B) Crownlike surface projections
C) Filamentous structures
D) Shepherd's hook

Question 10

Hemagglutinin and neuraminidase are surface glycoproteins associated with what family of viruses?

A) Parvovividae
B) Orthomyxoviridae
C) Picornaviridae
D) Caliciviridae

Question 11

One of the most pathogenic hemorrhagic fever viruses belongs to the _________ family.

A) Filoviridae
B) Flaviviridae
C) Papovaviridae
D) Picornaviridae

Question 12

MATCHING
Match the Flavivirus with its characteristics.
a.Yellow fever
b.Dengue fever
c.West Nile virus
d.Hepatitis C
Fever and leucopenia

Question 13

The term used to describe a virus that causes a global outbreak of serious illness of which little natural immunity exists and that has sustained person-to-person transmission is:

A) epidemic.
B) pandemic.
C) endemic.
D) widespread.

Question 14

This hemorrhagic fever causes disease in humans and nonhuman primates such as chimpanzees, gorillas, and monkeys.It is identified in the laboratory using which type of assay?

A) Immunodiffusion
B) Peptide nucleic acid fluorescence in situ hybridization (PNA-FISH)
C) Transcription-mediated amplification (TMA)
D) Reverse-transcriptase polymerase chain reaction (PCR)

Question 15

A 24-year-old woman is diagnosed with human papillomavirus (HPV)after having her annual Papanicolaou (Pap)smear.She was not vaccinated with the Gardasil vaccine.Which serotypes of the virus does she need to be concerned about that demonstrate the greatest risk for developing cervical cancer?

A) 12 and 14
B) 13 and 15
C) 16 and 18
D) 17 and 19

Question 16

A 45-year-old man living in the western United States begins experiencing headache, fever, and body aches, which he attributes to the flu.His symptoms, however, become worse, and he later develops kidney disease and acute respiratory failure.He is most likely infected with which virus?

A) Rabies virus
B) Adenovirus
C) Norovirus
D) Hantavirus

Question 17

Adenoviruses are responsible for causing diseases such as keratoconjunctivitis, pneumonia, hemorrhagic cystitis, and gastroenteritis in children.Transmission is usually via:

A) contact with rodent urine.
B) respiratory secretions.
C) arthropod vector.
D) sexual contact.

Question 18

Characteristics of which virus consist of a double-stranded genome and virions that appear as oval, brick-shaped structures of 200 to 400 nm in length? In addition, the World Health Organization (WHO)eradicated this virus in 1980.

A) Cowpox
B) Chickenpox
C) Swinepox
D) Smallpox

Question 19

Hantavirus classified in the Bunyaviridae family is transmitted via:

A) sandfly vector.
B) mosquito vector.
C) rodent excreta.
D) fecal-oral route.

Question 20

Which of the following highly contagious viruses is a single-stranded ribonucleic acid (RNA)virus with a helical capsid and envelope and is transmitted by coming in contact with respiratory secretions?

A) Coxsackievirus A
B) Rhinovirus
C) Parvovirus
D) Measles

Question 21

Match the virus with its symptoms and disease state.a.Herpes simplex virus (HSV) type 1
b.HSV type 2
c.Zoster
d.Varicella
e.Epstein-Barr virus (EBV)
f.CMV
g.Human herpesvirus (HHV) 8
Cold sore

Question 22

Match the disease with the corresponding Picornavirus.
a.Coxsackie A
b.Coxsackie B
Myocarditis

Question 23

Match the virus with its symptoms and disease state.a.Herpes simplex virus (HSV) type 1
b.HSV type 2
c.Zoster
d.Varicella
e.Epstein-Barr virus (EBV)
f.CMV
g.Human herpesvirus (HHV) 8
Kaposi sarcoma

Question 24

Match the disease with the corresponding Picornavirus.
a.Coxsackie A
b.Coxsackie B
Herpangina

Question 25

Match the disease with the corresponding Picornavirus.
a.Coxsackie A
b.Coxsackie B
Hand-foot-mouth

Question 26

Match the virus with its symptoms and disease state.a.Herpes simplex virus (HSV) type 1
b.HSV type 2
c.Zoster
d.Varicella
e.Epstein-Barr virus (EBV)
f.CMV
g.Human herpesvirus (HHV) 8
Chickenpox

Question 27

Match the virus with its symptoms and disease state.a.Herpes simplex virus (HSV) type 1
b.HSV type 2
c.Zoster
d.Varicella
e.Epstein-Barr virus (EBV)
f.CMV
g.Human herpesvirus (HHV) 8
Burkitt lymphoma

Question 28

Match the disease with the corresponding Picornavirus.
a.Coxsackie A
b.Coxsackie B
Pleurodynia

Question 29

Match the virus with its symptoms and disease state.a.Herpes simplex virus (HSV) type 1
b.HSV type 2
c.Zoster
d.Varicella
e.Epstein-Barr virus (EBV)
f.CMV
g.Human herpesvirus (HHV) 8
Shingles

Question 30

Match the virus with its symptoms and disease state.a.Herpes simplex virus (HSV) type 1
b.HSV type 2
c.Zoster
d.Varicella
e.Epstein-Barr virus (EBV)
f.CMV
g.Human herpesvirus (HHV) 8
Congenital disease

Question 31

Match the virus with its symptoms and disease state.a.Herpes simplex virus (HSV) type 1
b.HSV type 2
c.Zoster
d.Varicella
e.Epstein-Barr virus (EBV)
f.CMV
g.Human herpesvirus (HHV) 8
Genital

Question 32

MATCHING
Match the Flavivirus with its characteristics.
a.Yellow fever
b.Dengue fever
c.West Nile virus
d.Hepatitis C
Macropapular rash