Deck 21: Diuretic Drugs

Question 1

Diuretic resistance after chronic loop diuretic administration is due to:

A) Increase in the transport of organic cations from the blood to the urine
B) Increased Na⁺/K⁺ -ATPase activity
C) A decrease in Na⁺ reabsorption by distal tubule cells
D) Decreased osmotic load at the distal tubule
E) Decreased Na⁺/K⁺ -ATPase activity

Answer 1

Increased Na⁺/K⁺ -ATPase activity

Question 2

The location of the mechanism that leads to hypokalemia with many diuretics is located in the:

A) Glomerulus
B) Proximal convoluted tubule
C) Descending loop
D) Ascending loop
E) Collecting tubule

Answer 2

Collecting tubule

Question 3

Carbonic anhydrase inhibitors promote the excretion of Na⁺ and HCO₃‾, whereas thiazide diuretics promote:

A) Excretion of Na⁺, Cl‾, and Ca⁺⁺
B) Excretion of Na⁺ and Cl‾ while diminishing Ca⁺⁺ excretion
C) Excretion of Na⁺, Cl‾, Ca⁺⁺, and Mg⁺⁺
D) Excretion of Na⁺ and Cl‾ while reabsorbing Mg⁺⁺
E) Excretion of Na⁺ while diminishing Cl‾ excretion

Answer 3

Excretion of Na⁺ and Cl‾ while diminishing Ca⁺⁺ excretion