Deck 46: Antineoplastic Drugs Part 2: Cell Cyclenonspecific Drugs and Miscellaneous Drugs

Question 1

A patient is receiving a third session of chemotherapy with daunorubicin (Cerubidine). The nurse will assess the patient for which signs of a potential severe toxic effect of this drug?

A) Tinnitus and hearing loss
B) Numbness and tingling in the fingers
C) A weight gain of 2 pounds or more in 24 hours
D) Decreased blood urea nitrogen and creatinine levels

Answer 1

A weight gain of 2 pounds or more in 24 hours

Question 2

The nurse is hanging a new infusion bag of a chemotherapy drug, but the tubing becomes disconnected and a small amount of the solution drips onto the floor. Which action by the nurse is appropriate?

A) Let it dry, and then mop the floor.
B) Wipe the area with a disposable paper towel.
C) Use a spill kit to clean the area.
D) Ask the housekeeping department to clean the floor.

Answer 2

Use a spill kit to clean the area.

Question 3

What is the nurse's priority action if extravasation of an antineoplastic drug occurs during intravenous (IV) administration?

A) Reduce the infusion rate.
B) Discontinue the IV, and apply warm compresses.
C) Stop the infusion immediately, but leave the IV catheter in place.
D) Change the infusion to normal saline, and inject the area with hydrocortisone.

Answer 3

Stop the infusion immediately, but leave the IV catheter in place.

Question 4

During chemotherapy, a patient develops severe diarrhea caused by a vasoactive intestinal peptide-secreting tumor (VIPoma). The nurse expects to administer which drug for this problem?

A) Dexrazoxane (Zinecard)
B) Allopurinol (Zyloprim)
C) Octreotide (Sandostatin)
D) Bismuth subsalicylate (Pepto-Bismol)

Question 5

The nurse is assessing a patient who is receiving chemotherapy with an alkylating drug. Which assessment findings would be considered indications of an oncologic emergency?

A) Dry, "scratchy," or "swollen" throat
B) Loss of hair
C) Decreased red blood cell count
D) White patches in the mouth or throat
E) Temperature of 100.7° F (38.2° C)
F) Decreased urine output

Question 6

Just before the second course of chemotherapy, the laboratory calls to report that the patient's neutrophil count is 450 cells/mm³. The nurse expects that the oncologist will follow which course of treatment?

A) Chemotherapy will continue as scheduled.
B) Chemotherapy will resume with a lowered dosage.
C) Chemotherapy will resume after a transfusion of neutrophils.
D) Chemotherapy will be withheld until the neutrophil count returns toward normal levels.

Question 7

A patient will be receiving mitoxantrone (Novantrone), 12 mg/m²/day every 3 weeks, as part of treatment for prostate cancer. Each dose is mixed into a 50-mL bag of D₅W and needs to infuse over 15 minutes. The infusion pump delivers the dose at milliliters per hour. Identify the nurse will set the pump to infuse at what rate. _______

Question 8

When a patient is receiving cisplatin (Platinol-AQ) chemotherapy, the nurse will monitor for which adverse effects?

A) Tinnitus
B) Heart failure
C) Hearing loss
D) Elevated blood urea nitrogen and creatinine levels
E) Numbness or tingling in the extremities
F) Elevated glucose and ketone levels

Question 9

A female patient is receiving palliative therapy with androgen hormones as part of treatment for inoperable breast cancer. The nurse will discuss with the patient which potential body image changes that may occur as adverse effects?

A) Hirsutism and acne
B) Weight gain
C) Flushing and hot flashes
D) Alopecia and body odor

Question 10

The nurse is teaching a class about the various chemotherapy drugs. Which of these statements explains why alkylating drugs are also called "cell cycle-nonspecific drugs"?

A) They are cytotoxic during a specific cell cycle.
B) They are cytotoxic in any phase of the cell cycle.
C) They are effective against several types of neoplasms.
D) They are more highly differentiated than cell cycle-specific drugs.

Question 11

When giving cisplatin (Platinol-AQ), the nurse is aware that adverse effect of this drug is which condition?

A) Alopecia
B) Kidney damage
C) Cardiotoxicity
D) Stomatitis

Question 12

A patient is receiving doxorubicin (Adriamycin) as part of treatment for ovarian cancer. Which of these is a possible adverse effect of doxorubicin?

A) Cardiotoxicity
B) Pulmonary toxicity
C) Neurotoxicity
D) Hyperuricemia