Deck 19: Regulation of Metabolism
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Deck 19: Regulation of Metabolism
1
Which of the following minerals is needed only in trace amounts by the body?
A)sodium
B)potassium
C)iron
D)calcium
A)sodium
B)potassium
C)iron
D)calcium
C
2
Which of the following is NOT an essential amino acid?
A)leucine
B)valine
C)lysine
D)proline
A)leucine
B)valine
C)lysine
D)proline
D
3
Individuals consuming diets containing omega-3 fatty acids are less likely to develop cardiovascular disease.
True
4
Wound healing would be delayed due to a lack of
A) vitamin E.
B) vitamin C.
C) potassium.
D) vitamin A.
A) vitamin E.
B) vitamin C.
C) potassium.
D) vitamin A.
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5
Which of the following is NOT a function of derivatives of water-soluble vitamins?
A)coenzymes in metabolism of carbohydrates, lipids, and proteins
B)forming hydrogen carriers NAD and FAD
C)cofactors for enzymes
D)intestinal absorption of calcium and phosphate
A)coenzymes in metabolism of carbohydrates, lipids, and proteins
B)forming hydrogen carriers NAD and FAD
C)cofactors for enzymes
D)intestinal absorption of calcium and phosphate
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6
One gram of fat contains more energy than 2 grams of protein.
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7
Which of the following acts as an antioxidant within the body?
A)vitamin C
B)vitamin A
C)vitamin K
D)niacin
A)vitamin C
B)vitamin A
C)vitamin K
D)niacin
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8
Blood clotting requires
A) vitamin C.
B) vitamin D.
C) vitamin K.
D) vitamin E.
A) vitamin C.
B) vitamin D.
C) vitamin K.
D) vitamin E.
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9
Fatty acids which have double bonds between the carbons are called saturated fatty acids.
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10
Strict vegetarians may be susceptible to
A)pernicious anemia.
B)night blindness.
C)pellagra.
D)scurvy.
A)pernicious anemia.
B)night blindness.
C)pellagra.
D)scurvy.
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11
The main factor determining differences in energy requirements of individuals of similar gender and weight is the difference in
A)physical activity.
B)genetics.
C)body temperature.
D)height.
A)physical activity.
B)genetics.
C)body temperature.
D)height.
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12
If an individual consumes excess calories in the form of carbohydrates, the excess energy is stored as
A)glycogen.
B)structural carbohydrates.
C)fat.
D)skeletal muscle.
A)glycogen.
B)structural carbohydrates.
C)fat.
D)skeletal muscle.
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13
Which of the following is NOT a fat-soluble vitamin?
A)vitamin E
B)vitamin A
C)vitamin C
D)vitamin D
A)vitamin E
B)vitamin A
C)vitamin C
D)vitamin D
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14
The vitamin D derivative calcipotriene is used to treat the skin condition
A)pellagra.
B)beriberi.
C)scurvy.
D)psoriasis.
A)pellagra.
B)beriberi.
C)scurvy.
D)psoriasis.
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15
The metabolic rate of an awake, relaxed person, 12 to 14 hours after eating, at a comfortable temperature is known as the
A)average metabolic rate.
B)basal metabolic rate.
C)oxidative metabolic rate.
D)metabolic rate.
A)average metabolic rate.
B)basal metabolic rate.
C)oxidative metabolic rate.
D)metabolic rate.
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16
A positive energy balance occurs when
A)energy expenditures are greater than the calorie value of food.
B)energy expenditures balance the calorie value of food.
C)the calorie value of food is greater than energy expenditures.
D)you lose weight.
A)energy expenditures are greater than the calorie value of food.
B)energy expenditures balance the calorie value of food.
C)the calorie value of food is greater than energy expenditures.
D)you lose weight.
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17
Which of the following is NOT true of oxidative stress?
A)protects from development of type 2 diabetes mellitus.
B)contributes to aging and degenerative diseases associated with aging.
C)promotes the malignant growth of cancers.
D)contributes to all inflammatory diseases.
A)protects from development of type 2 diabetes mellitus.
B)contributes to aging and degenerative diseases associated with aging.
C)promotes the malignant growth of cancers.
D)contributes to all inflammatory diseases.
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18
Metabolic rate can be measured by the
A)amount of heat generated by the body.
B)heart and respiration rates.
C)amount of oxygen consumed by the body.
D)amount of heat generated and the amount of oxygen consumed by the body.
A)amount of heat generated by the body.
B)heart and respiration rates.
C)amount of oxygen consumed by the body.
D)amount of heat generated and the amount of oxygen consumed by the body.
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19
Which vitamin and its deficiency is NOT correctly matched?
A)vitamin B1 - beriberi
B)folate - pernicious anemia
C)niacin - pellagra
D)vitamin D - rickets
A)vitamin B1 - beriberi
B)folate - pernicious anemia
C)niacin - pellagra
D)vitamin D - rickets
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20
There are nine essential amino acids and 2 essential fatty acids.
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21
Exercising at low or moderate intensity promotes use of fatty acids by skeletal muscle.
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22
Destruction of which cell type in the fetus would affect adipocyte number in the adult?
A)myoblasts
B)neuroblasts
C)epiblasts
D)fibroblasts
A)myoblasts
B)neuroblasts
C)epiblasts
D)fibroblasts
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23
Oxidative stress is associated with many diseases because of the buildup of free radicals in the nucleus of aerobic cells.
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24
Which of the following is NOT an enzymatic protection against oxidative stress?
A)catalase
B)superoxide dismutase
C)alpha-tocopherol
D)glutathioneperoxidase
A)catalase
B)superoxide dismutase
C)alpha-tocopherol
D)glutathioneperoxidase
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25
The nuclear receptor protein required for differentiation of ________ is PPARy (perioxisome proliferator activated receptor y).
A)erythrocytes
B)fibroblasts
C)adipocytes
D)reticulocytes
A)erythrocytes
B)fibroblasts
C)adipocytes
D)reticulocytes
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26
Insulin resistance may be stimulated by elevated concentrations of all of the following EXCEPT
A)tumor necrosis factor alpha.
B)resistin.
C)adiponectin.
D)retinol binding protein 4.
A)tumor necrosis factor alpha.
B)resistin.
C)adiponectin.
D)retinol binding protein 4.
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27
Which of the following are NOT roles of leptin?
A)decline in helper T abilities
B)regulate onset of puberty
C)menstrual abnormalities
D)increased hunger
A)decline in helper T abilities
B)regulate onset of puberty
C)menstrual abnormalities
D)increased hunger
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28
Superoxide radicals have which of the following beneficial effects?
A)killing bacteria
B)promote proliferation of fibroblasts
C)promote proliferation of lymphocytes
D)All of the choices are correct.
A)killing bacteria
B)promote proliferation of fibroblasts
C)promote proliferation of lymphocytes
D)All of the choices are correct.
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29
The preferred energy source for resting skeletal muscle is (are)
A)glucose.
B)glycogen.
C)fatty acids.
D)protein.
A)glucose.
B)glycogen.
C)fatty acids.
D)protein.
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30
Primary energy reserves include glycogen and fat.
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31
The nitric oxide radical promotes vasodilation.
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32
Which of the following is NOT a circulating energy substrate?
A)glucose
B)glycogen
C)fatty acids
D)amino acids
A)glucose
B)glycogen
C)fatty acids
D)amino acids
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33
The risk of cardiovascular disease is increased
A)in someone with a "pear shaped" body.
B)in someone with an "apple shaped" body.
C)in someone with a BMI less than 30.
D)in someone with little intraabdominal fat.
A)in someone with a "pear shaped" body.
B)in someone with an "apple shaped" body.
C)in someone with a BMI less than 30.
D)in someone with little intraabdominal fat.
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34
__________ is an adipose tissue hormone that stimulates glucose utilization and fatty acid oxidation in muscle cells thereby producing an insulin-sensitizing, antidiabetic effect.
A)Leptin
B)Adiponectin
C)TNF alpha
D)Resistin
A)Leptin
B)Adiponectin
C)TNF alpha
D)Resistin
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35
A free radical has
A)paired electrons.
B)unpaired electrons.
C)unbonded electrons.
D)bonded electrons.
A)paired electrons.
B)unpaired electrons.
C)unbonded electrons.
D)bonded electrons.
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36
Low leptin levels are found in cases of starvation, anorexia, and bulimia.
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37
Tissue damage by free radicals is prevented to some extent by all of the following EXCEPT
A) beta-carotene.
B) vitamin C.
C) vitamin D.
D) vitamin E.
A) beta-carotene.
B) vitamin C.
C) vitamin D.
D) vitamin E.
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38
Obesity in adults results primarily from adipocyte hyperplasia.
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39
Excessive production of free radicals that can damage lipids, proteins, and DNA is called
A)inflammation.
B)antioxidation.
C)oxidative stress.
D)quenching.
A)inflammation.
B)antioxidation.
C)oxidative stress.
D)quenching.
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40
Which of the following is NOT a nonenzymatic protection against oxidative stress?
A)hydrogen peroxide
B)glutathione
C)ascorbic acid
D)alpha-tocopherol
A)hydrogen peroxide
B)glutathione
C)ascorbic acid
D)alpha-tocopherol
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41
Starvation decreases metabolic rate by as much as
A)10%.
B)20%.
C)40%.
D)65%.
A)10%.
B)20%.
C)40%.
D)65%.
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42
Which of the following is NOT true of metabolic syndrome?
A)hypotension
B)insulin resistance
C)dyslidipemia
D)central obesity
A)hypotension
B)insulin resistance
C)dyslidipemia
D)central obesity
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43
One of the factors that increases body heat during adaptive thermogenesis is the production of ___________ by skeletal muscle.This product causes leakage of protons from the intermembrane space of the mitochondria.
A)uncoupling protein
B)insulin
C)glycogen
D)glucagon
A)uncoupling protein
B)insulin
C)glycogen
D)glucagon
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44
Which of the following components of energy expenditure is greatest in an average, sedentary adult?
A)basal metabolic rate.
B)adaptive thermogenesis.
C)physical activity.
D)None of the choices are correct.
A)basal metabolic rate.
B)adaptive thermogenesis.
C)physical activity.
D)None of the choices are correct.
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45
A female with a BMI of 25.0 would be considered
A)obese.
B)overweight.
C)healthy.
D)too thin.
A)obese.
B)overweight.
C)healthy.
D)too thin.
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46
Satiety would be induced by all of the following EXCEPT
A)cholecystokinin.
B)naloxone.
C)morphine.
D)serotonin.
A)cholecystokinin.
B)naloxone.
C)morphine.
D)serotonin.
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47
Fat cells are less sensitive to insulin in
A)obese individuals.
B)anorexic individuals.
C)individuals who do not exercise.
D)individuals at their optimal weight.
A)obese individuals.
B)anorexic individuals.
C)individuals who do not exercise.
D)individuals at their optimal weight.
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48
Ghrelin is postulated to be important as a satiety factor.
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49
A BMI of over ____ is considered obese.
A)20
B)25
C)30
D)35
A)20
B)25
C)30
D)35
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50
Which of the following are involved in long-term regulation of hunger?
A)leptin and CCK
B)ghrelin and CCK
C)insulin and PYY
D)leptin and insulin
A)leptin and CCK
B)ghrelin and CCK
C)insulin and PYY
D)leptin and insulin
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51
The BMI of a female weighing 130 pounds with a height of 68 inches would be
A)2.4
B)20.4
C)76.5
D)34.8
A)2.4
B)20.4
C)76.5
D)34.8
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52
A tumor suppressing the activity of which brain area could induce obesity?
A)ventromedial hypothalamus
B)lateral hypothalamus
C)dorsomedial hypothalamus
D)anterior hypothalamus
A)ventromedial hypothalamus
B)lateral hypothalamus
C)dorsomedial hypothalamus
D)anterior hypothalamus
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53
The arcuate nucleus is a region of the thalamus involved in hunger regulation.
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54
Activation of the sympathoadrenal system would cause
A)hypoglycemia.
B)diabetes insipidus.
C)hyperglycemia.
D)excessive weight gain.
A)hypoglycemia.
B)diabetes insipidus.
C)hyperglycemia.
D)excessive weight gain.
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55
Ablation of the thyroid gland would cause a drop in basal metabolic rate.
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56
To decrease hunger, MSH must bind to its receptor, ______ in the arcuate nucleus of the hypothalamus.
A)neuropeptide Y
B)agouti-related protein
C)melanocortin 4
D)PYY
A)neuropeptide Y
B)agouti-related protein
C)melanocortin 4
D)PYY
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57
Hyperphagia is produced by destroying the ventromedial area of the hypothalamus.
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58
_______ is a satiety factor that acts to suppress neuropeptide Y and stimulate MSH release.
A)Leptin
B)MSH
C)Glucose
D)Insulin
A)Leptin
B)MSH
C)Glucose
D)Insulin
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59
Adaptive thermogenesis is the heat energy expended by the body in response to all of the following EXCEPT
A)increase in ambient temperature.
B)digestion of food.
C)physical activity.
D)decrease in ambient temperature.
A)increase in ambient temperature.
B)digestion of food.
C)physical activity.
D)decrease in ambient temperature.
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60
Which of the following are involved in short-term regulation of hunger?
A)leptin and CCK
B)ghrelin and CCK
C)insulin and PYY
D)leptin and insulin
A)leptin and CCK
B)ghrelin and CCK
C)insulin and PYY
D)leptin and insulin
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61
Lipolysis is increased by
A)epinephrine.
B)growth hormone.
C)glucagon.
D)All of the choices are correct.
A)epinephrine.
B)growth hormone.
C)glucagon.
D)All of the choices are correct.
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62
The effects of glucagon are _____________ by insulin.
A)enhanced
B)opposed
C)synergized
D)agonized
A)enhanced
B)opposed
C)synergized
D)agonized
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63
Insulin secretion is stimulated by _____________ blood glucose concentrations.
A)increased
B)decreased
C)unchanged
A)increased
B)decreased
C)unchanged
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64
Destruction of which pancreatic cells would cause hyperglycemia?
A)alpha cells
B)beta cells
C)delta cells
D)None of the choices are correct.
A)alpha cells
B)beta cells
C)delta cells
D)None of the choices are correct.
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65
Which of the following increase(s) lipogenesis?
A)insulin
B)growth hormone
C)glucagon
D)All of the choices are correct.
A)insulin
B)growth hormone
C)glucagon
D)All of the choices are correct.
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66
Elevated blood glucose triggers insulin secretion.
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67
Which hormone has no effect on blood glucose levels?
A)insulin
B)thyroid hormone
C)growth hormone
D)epinephrine
A)insulin
B)thyroid hormone
C)growth hormone
D)epinephrine
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68
The oral glucose test is a measure of the ability of the alpha cells to secrete insulin and of the ability of insulin to increase blood glucose levels.
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69
During the absorptive state, catabolic reactions are favored over anabolic reactions.
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70
Lipolysis and gluconeogenesis are stimulated when
A)insulin and glucagon are both decreasing.
B)insulin and glucagon are both increasing.
C)insulin is increasing and glucagon is decreasing.
D)insulin is decreasing and glucagon is increasing.
A)insulin and glucagon are both decreasing.
B)insulin and glucagon are both increasing.
C)insulin is increasing and glucagon is decreasing.
D)insulin is decreasing and glucagon is increasing.
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71
What is the major function of brown adipose tissue?
A)shivering thermogenesis
B)nonshivering thermogenesis
C)decreasing metabolic rate
D)decrease body temperature
A)shivering thermogenesis
B)nonshivering thermogenesis
C)decreasing metabolic rate
D)decrease body temperature
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72
Stress hyperglycemia results from the effects of epinephrine and glucagon.
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73
Insulin promotes cellular uptake of glucose by inserting these channels into plasma membranes.
A)uncoupling protein
B)glucagon
C)Glut4
D)leptin
A)uncoupling protein
B)glucagon
C)Glut4
D)leptin
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74
Which of the following is NOT a caloric energy expenditure of the body?
A)BMI
B)physical activity
C)BMR
D)adaptive thermogenesis
A)BMI
B)physical activity
C)BMR
D)adaptive thermogenesis
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75
Destruction of the alpha cells of the pancreas would decrease glucagon secretion.
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76
____________ is made by the delta cells of the pancreas.
A)Glucose
B)Somatostatin
C)Glucagon
D)All of the choices are correct.
A)Glucose
B)Somatostatin
C)Glucagon
D)All of the choices are correct.
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77
Epinephrine increases lipolysis and ketogenesis.
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78
The hormone that antagonizes the effect of growth hormone is
A)glucagon.
B)thyroxin.
C)insulin.
D)epinephrine.
A)glucagon.
B)thyroxin.
C)insulin.
D)epinephrine.
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79
Elevated concentrations of glucagon would result in
A)decreased lipolysis.
B)decreased glycogen synthesis.
C)increased gluconeogenesis.
D)increased lipogenesis.
A)decreased lipolysis.
B)decreased glycogen synthesis.
C)increased gluconeogenesis.
D)increased lipogenesis.
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80
What hormone is important in adaptive thermogenesis?
A)calcitonin
B)thyroxine
C)insulin
D)MSH
A)calcitonin
B)thyroxine
C)insulin
D)MSH
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