Deck 28: Nucleic Acids
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Deck 28: Nucleic Acids
1
Which of the following is D-ribose? 
A)1
B)2
C)3
D)4

A)1
B)2
C)3
D)4
1
2
What is the approximate distance between stacked bases in a double helix of DNA?
A)340 pm
B)800 pm
C)2000 pm
D)3400 pm
A)340 pm
B)800 pm
C)2000 pm
D)3400 pm
340 pm
3
Which of the following is 2-deoxy-D-ribose? 
A)1
B)2
C)3
D)4

A)1
B)2
C)3
D)4
2
4
Which of the following is uridine? 
A)1
B)2
C)3
D)4

A)1
B)2
C)3
D)4
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5
What tetrapeptide is coded by the following sequence of mRNA? 5'-AUG-GUA-AUG-UUG-3'
A)Met-Val-Met-Leu
B)Ala-Val- Leu-Met
C)Met-Val-Ala-Leu
D)Ala-Ala-Met-Leu
A)Met-Val-Met-Leu
B)Ala-Val- Leu-Met
C)Met-Val-Ala-Leu
D)Ala-Ala-Met-Leu
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6
Which of the following is a purine base?
A)uracil
B)cytosine
C)thymine
D)adenine
A)uracil
B)cytosine
C)thymine
D)adenine
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7
Which of the following is a definition of a codon?
A)a complimentary pair of hydrogen bonded bases in RNA
B)a sequence of three bases on RNA that directs incorporation of a specific amino acid into a protein
C)a complex between DNA and RNA
D)RNA found in the ribosome, the site in cells where synthesis of proteins takes place
A)a complimentary pair of hydrogen bonded bases in RNA
B)a sequence of three bases on RNA that directs incorporation of a specific amino acid into a protein
C)a complex between DNA and RNA
D)RNA found in the ribosome, the site in cells where synthesis of proteins takes place
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8
Which of the following is deoxyadenosine? 
A)1
B)2
C)3
D)4

A)1
B)2
C)3
D)4
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9
What is the approximate diameter of double helix of DNA?
A)340 pm
B)800 pm
C)2000 pm
D)3400 pm
A)340 pm
B)800 pm
C)2000 pm
D)3400 pm
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10
What is the approximate length of a complete turn of a double helix of DNA?
A)340 pm
B)800 pm
C)2000 pm
D)3400 pm
A)340 pm
B)800 pm
C)2000 pm
D)3400 pm
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11
Which of the following is a definition of messenger RNA (mRNA)?
A)RNA found in the ribosome, the site in cells where synthesis of proteins takes place
B)RNA which carries a specific amino acid to the site of protein synthesis
C)RNA which has coded genetic information
D)RNA which signals cell death
A)RNA found in the ribosome, the site in cells where synthesis of proteins takes place
B)RNA which carries a specific amino acid to the site of protein synthesis
C)RNA which has coded genetic information
D)RNA which signals cell death
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12
What sequence is fully complementary to the following sequence? 5'-ATCTAGTCA-3'
A)5'-TAGATCAGT-3'
B)5'-TGACTAGAT-3'
C)5'-ATCTAGTCA-3
D)5'-ACTGATCTA-3'
A)5'-TAGATCAGT-3'
B)5'-TGACTAGAT-3'
C)5'-ATCTAGTCA-3
D)5'-ACTGATCTA-3'
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13
Which of the following is a complimentary pair of hydrogen-bonded bases found in RNA?
A)A - C
B)A - G
C)A - T
D)A - U
A)A - C
B)A - G
C)A - T
D)A - U
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14
How many bases are present in each strand of a complete turn of B-DNA?
A)3
B)7
C)10
D)15
A)3
B)7
C)10
D)15
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15
Which of the following is a complimentary pair of hydrogen-bonded bases found in DNA?
A)A - C
B)A - G
C)A - T
D)A - U
A)A - C
B)A - G
C)A - T
D)A - U
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16
Where is the amino acid linked to the ribose unit of transfer RNA in the process of transferring the amino acid to ribosomes?
A)the base
B)C2'-OH
C)3'-OH
D)5'-OH
A)the base
B)C2'-OH
C)3'-OH
D)5'-OH
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17
Which of the following is a definition of transfer RNA (tRNA)?
A)RNA found in the ribosome, the site in cells where synthesis of proteins takes place
B)RNA which carries a specific amino acid to the site of protein synthesis
C)RNA which has coded genetic information
D)RNA which allows transfer of a protein out of a cell
A)RNA found in the ribosome, the site in cells where synthesis of proteins takes place
B)RNA which carries a specific amino acid to the site of protein synthesis
C)RNA which has coded genetic information
D)RNA which allows transfer of a protein out of a cell
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18
What sequence is fully complementary to the following sequence? 5'-GTACGACT-3'
A)5'-GTACGACT-3'
B)5'-TCAGCATG-3'
C)5'-AGTCGTAC-3"
D)5'-CATGCTGA-3'
A)5'-GTACGACT-3'
B)5'-TCAGCATG-3'
C)5'-AGTCGTAC-3"
D)5'-CATGCTGA-3'
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19
What is the function of an endonuclease?
A)cleavage of a specific base from DNA
B)cleavage of a specific phosphodiester bond in DNA
C)promotion of folding of DNA into a double helix
D)carrying a specific amino acid to the site of protein synthesis
A)cleavage of a specific base from DNA
B)cleavage of a specific phosphodiester bond in DNA
C)promotion of folding of DNA into a double helix
D)carrying a specific amino acid to the site of protein synthesis
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20
Which of the following is a pyrimidine base?
A)guanine
B)adenine
C)thymine
D)triethylamine
A)guanine
B)adenine
C)thymine
D)triethylamine
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21
MATCH each of the following terms to a structure from the list below. There is only one correct answer for each question and structures may be used more than once. Place the letter of the structure in the blank to the left of the corresponding term.
_____ is a DNA base sequence with cytosine at the 3' end.
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)
F)
G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)
L)
M)AGATCGCTC
_____ is a DNA base sequence with cytosine at the 3' end.
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)

F)

G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)

L)

M)AGATCGCTC
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22
Relative to the secondary structure of DNA, there is no restriction on the sequence of bases along a polynucleotide chain. The exact sequence carries the genetic information.
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23
MATCH each of the following terms to a structure from the list below. There is only one correct answer for each question and structures may be used more than once. Place the letter of the structure in the blank to the left of the corresponding term.
_____ is a RNA base sequence with guanine at the 3' end.
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)
F)
G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)
L)
M)AGATCGCTC
_____ is a RNA base sequence with guanine at the 3' end.
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)

F)

G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)

L)

M)AGATCGCTC
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24
The structural arrangement of DNA is 

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25
The name of the following nucleotide is_____________________________. 

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26
The structure of the sugar in RNA is shown below. 

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27
Relative to the secondary structure of DNA, the helices are left handed and the two strands run in same directions relative to their 3'and 5' ends.
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28
MATCH each of the following terms to a structure from the list below. There is only one correct answer for each question and structures may be used more than once. Place the letter of the structure in the blank to the left of the corresponding term.
_____ is uridine.
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)
F)
G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)
L)
M)AGATCGCTC
_____ is uridine.
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)

F)

G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)

L)

M)AGATCGCTC
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29
A correct abbreviation for the following nucleotide is ADP.

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30
MATCH each of the following terms to a structure from the list below. There is only one correct answer for each question and structures may be used more than once. Place the letter of the structure in the blank to the left of the corresponding term.
_____ is the DNA sequencing method for the human genome.
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)
F)
G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)
L)
M)AGATCGCTC
_____ is the DNA sequencing method for the human genome.
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)

F)

G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)

L)

M)AGATCGCTC
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31
MATCH each of the following terms to a structure from the list below. There is only one correct answer for each question and structures may be used more than once. Place the letter of the structure in the blank to the left of the corresponding term.
_____ is a pyrimidine nucleoside.
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)
F)
G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)
L)
M)AGATCGCTC
_____ is a pyrimidine nucleoside.
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)

F)

G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)

L)

M)AGATCGCTC
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32
The following structures is a pyrimidine. 

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33
Relative to the secondary structure of DNA, the purine and pyrimidine bases lie inside the helix, in planes perpendicular to the helical axis; the deoxyribose and phosphate groups form the outside of the helix.
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34
MATCH each of the following terms to a structure from the list below. There is only one correct answer for each question and structures may be used more than once. Place the letter of the structure in the blank to the left of the corresponding term.
-_____ is the RNA base sequence complementary to the DNA base sequence shown below which codes for Leu-Ala-Phe.
CTAGCATTT
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)
F)
G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)
L)
M)AGATCGCTC
-_____ is the RNA base sequence complementary to the DNA base sequence shown below which codes for Leu-Ala-Phe.
CTAGCATTT
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)

F)

G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)

L)

M)AGATCGCTC
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35
The G-C base pair is the weaker than the A-T base pair as it has two hydrogen bonds whereas the A-T base pair has three.
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36
If ranked for largest to smallest, the correct order of DNA, mRNA, and tRNA would be DNA > mRNA > tRNA.
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37
The structure below represents a nucleoside. 

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38
The name of the base in the following nucleotide is __________________. 

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39
MATCH each of the following terms to a structure from the list below. There is only one correct answer for each question and structures may be used more than once. Place the letter of the structure in the blank to the left of the corresponding term.
_____ is process by which mRNA directs protein synthesis.
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)
F)
G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)
L)
M)AGATCGCTC
_____ is process by which mRNA directs protein synthesis.
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)

F)

G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)

L)

M)AGATCGCTC
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40
A three base sequence called a "codon" codes for one _______________.
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41
Provide the structure of adenosine, a nucleoside.
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42
Provide the structure of 2-deoxyribose.
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43
Provide the structure of cytidine 5'-monophosphate, a nucleotide consisting of a cytosine base, a ribose and a phosphate group.
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44
A double-stranded DNA molecule that contains 22%, on a mole basis, T must also contain ___% G.
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45
Provide the structure of a G-C base pair, showing hydrogen bonds as dotted lines.
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46
Number each position in the ribose below according to the normal convention. 

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47
Provide the structure of adenosine triphosphate, ATP.
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48
What sequence is fully complementary to the following sequence?
5'-TAGCGATC-3'
5'-TAGCGATC-3'
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49
What sequence is fully complementary to the following sequence?
5'-AGTCAATTC-3'
5'-AGTCAATTC-3'
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50
Provide the structure of a T-A base pair, showing hydrogen bonds as dotted lines.
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51
MATCH each of the following terms to a structure from the list below. There is only one correct answer for each question and structures may be used more than once. Place the letter of the structure in the blank to the left of the corresponding term.
_____ is a pyrimidine nucleoside.
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)
F)
G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)
L)
M)AGATCGCTC
_____ is a pyrimidine nucleoside.
A)Sanger dideoxy method
B)GAUCGUAAA
C)Watson-Crick
D)translation
E)

F)

G)transcription
H)Maxam-Gilbert method
I)AUGGCUGAG
J)replication
K)

L)

M)AGATCGCTC
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52
Provide the structure of guanine, a heterocyclic base found in DNA.
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