The Critical Care Nurse Is Delivering a Peer Lecture on Guidelines

The critical care nurse is delivering a peer lecture on guidelines for the management of SIRS and severe sepsis. Which intervention would the nurse describe as improving outcomes in septic shock?

A) Use bicarbonate for pH of 7.30.
B) Keep mechanically ventilated patients flat in bed.
C) Maintain blood glucose lower than 150 mg/dL.
D) Initiate antibiotic therapy within 4 hours of diagnosis.