A nitrile can be made by dehydrating an amide. However, for this reaction to occur, the amide must be ________.

Name: A nitrile can be made by dehydrating an amide. However, for this reaction to occur, the amide must be ________.
Brand: Quizplus
Rating: 4.9 (62 reviews)

Question

Quizplus · Accepted Answer

Only primary amides can be dehydrated to form nitriles. Secondary and tertiary amides do not undergo this reaction. N-methylation and lactam formation would also prevent the amide from being able to dehydrate to form a nitrile.

A Nitrile Can Be Made by Dehydrating an Amide