When a 1° amine reacts with an alkyl sulfonyl chloride, the major organic product is ________.
A) a tosylhydrazone
B) a nitrile
C) a sulfoxide
D) an oxime
E) a sulfonamide

Question

Quizplus · Accepted Answer

When a 1° amine reacts with an alkyl sulfonyl chloride, the major organic product is a sulfonamide. This reaction is known as the Gabriel synthesis, and it is a method for introducing an amino group into a molecule. The sulfonamide product is useful for further synthetic transformations, as well as in medicinal chemistry.

When a 1° Amine Reacts with an Alkyl Sulfonyl Chloride