Which of the following alkyl halides reacts most rapidly via an S_N2 reaction with NaCN? A) 1-iodohexane B) 1-fluorohexane C) (R)-2-bromohexane D) iodocyclohexane E) 1-iodo-1-methylcyclohexane

Question

Quizplus · Accepted Answer

1-Iodohexane is a primary alkyl halide, which is less hindered and more reactive in S_N2 reactions compared to secondary or tertiary alkyl halides. Additionally, iodine is a better leaving group than fluorine, making 1-iodohexane the most reactive in an S_N2 reaction.

Which of the Following Alkyl Halides Reacts Most Rapidly Via