A patient will be receiving nitrofurantoin (Macrodantin)treatment for a urinary tract infection.The nurse is reviewing the patient's history and will question the nitrofurantoin order if which disorder is present in the history? (Select all that apply.)

Question

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Nitrofurantoin is contraindicated in patients with significant renal impairment (chronic renal disease) because it requires adequate kidney function for excretion. Liver disease is also a concern as it can affect drug metabolism and increase the risk of toxicity.

A Patient Will Be Receiving Nitrofurantoin (Macrodantin)treatment for a Urinary