A client with a pituitary defect is being treated for Addison disease with supplemental corticosteroids. The client develops signs and symptoms of Cushing syndrome. Which of the following is the mechanism responsible for this syndrome?

Question

Quizplus · Accepted Answer

The development of Cushing syndrome in this context is due to the disruption of feedback mechanisms. Excessive corticosteroid supplementation can suppress the hypothalamic-pituitary-adrenal axis, leading to decreased ACTH production and subsequent symptoms of Cushing syndrome.

A Client with a Pituitary Defect Is Being Treated for Addison