A client is receiving an antiviral drug that is a substrate of the CYP3A4 enzyme system. A drug that is an inhibitor of the 3A4 system is added to the client's regimen. What result will the nurse assess the client for?

Question

Quizplus · Accepted Answer

Inhibitors of the CYP3A4 enzyme system can increase the concentration of drugs that are metabolized by this pathway, leading to potential toxicity. Thus, the nurse should assess the client for signs and symptoms of toxicity of the antiviral drug.

A Client Is Receiving an Antiviral Drug That Is a Substrate