(S)-Naproxen,[$\alpha$]_D= + 66$\degree$,is an analgesic (pain reliever),while its enantiomer is toxic.Say that you were given a solution that contains 1 g of Naproxen in 20 mL of liquid,but the optical purity is not specified.You place it in a polarimeter tube (10 cm)and get a reading of + 3.3$\degree$ from the polarimeter.What is the percent optical purity of the sample?

Question

Quizplus · Accepted Answer

The specific rotation of pure (S)-Naproxen is +66. The observed rotation is +3.3. The percent optical purity is therefore (3.3/66) * 100 = 5%.

(S)-Naproxen,[ α\alphaα ]D = + 66 °\degree° ,Is an Analgesic (Pain Reliever),while Its Enantiomer Is Toxic

(S)-Naproxen,[ $\alpha$ ]_D= + 66 $\degree$ ,Is an Analgesic (Pain Reliever),while Its Enantiomer Is Toxic