Infants have decreased plasma protein-binding sites because of decreased plasma protein and albumin levels. With drugs that are highly protein bound, how should the drug dose for infants be different from that for adults?

Question

Quizplus · Accepted Answer

With fewer protein-binding sites, there is more active drug available. This requires a reduction in the dose for infants.

Infants Have Decreased Plasma Protein-Binding Sites Because of Decreased Plasma