A client is taking a drug that is moderately highly protein bound. Several days later, the client takes a second drug that is 90% protein bound. What is most likely to have occurred as a result of this administration?

Question

Quizplus · Accepted Answer

Only drugs not bound to protein are active and can cause a pharmacologic response. As the free drug in the circulation decreases, more bound drug is released from the protein to maintain the balance of free drug.

A Client Is Taking a Drug That Is Moderately Highly