The following sequence represents the steps in the biosynthesis of fatty acids.
Step
Type of Reaction
1
nucleophilic acyl substitution
2
nucleophilic acyl substitution
3
carboxylation
4
nucleophilic acyl substitution
5
condensation
6
reduction
7
dehydration
8
reduction
a)In which step is the new carbon−carbon bond that builds the fatty acid chain formed?
b)In which step does the following reaction occur?
c)
Complete the reaction below by giving the species that should be placed in each box.
d)
In which step is the mechanism identical to the conversion of pyruvate to oxaloacetate in gluconeogenesis?
e)
In what respect are steps 1 and 2 identical to steps 3 and 4?
f)
In which step is the butyryl group formed?
Correct Answer:
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b)3, carboxy...
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