Which of the following have the S configuration? A B C

Question

Which of the following have the S configuration? A  B  C  ​
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Quizplus · Accepted Answer

The S configuration refers to the stereochemistry of a chiral center or stereocenter. A chiral center is an atom in a molecule that has four different groups bonded to it. In order to determine the S configuration, you need to understand the Cahn-Ingold-Prelog (CIP) priority rules, which assign a priority to each group based on the atomic number of the atoms directly bonded to the chiral center.

Using the CIP priority rules, you can determine that for A, the lowest priority group (TB6688_00) is pointing away from you, which means that the remaining three groups (11eab600_0888_805b_9625_c308306f6913, H, and OH) are arranged in a clockwise fashion. This gives A the S configuration.

Similarly, for B, the lowest priority group (TB6688_00) is pointing away from you, and the remaining three groups (11eab600_0888_805c_9625_bbedb20806a4, H, and OH) are arranged counterclockwise. This inversion of chirality gives B the S configuration.

Finally, for C, the lowest priority group (TB6688_00) is pointing toward you, which means that the remaining three groups (11eab600_0888_a76d_9625_cb9253c78b0f, H, and OH) are arranged in a counterclockwise fashion. This gives C the R configuration.

Therefore, only A and B have the S configuration.

Which of the Following Have the S Configuration? a