Your Patient Is a 36-Year-Old Female, Conscious and Alert, Sitting

Your patient is a 36-year-old female, conscious and alert, sitting at her desk and complaining of a rash and itchiness after taking a sulfa antibiotic. Physical examination reveals warm and dry skin, urticaria on her chest and back, lung sounds that are clear and equal bilaterally. HR = 100, BP = 132/78, RR = 14, SaO₂ = 98%. Which of the following is the most appropriate treatment for this patient?

A) Oxygen via nasal cannula, IV crystalloid solution, 5 mg epinephrine IV, 25 mg diphenhydramine IV
B) Transport only
C) Oxygen via nonrebreather mask, IV crystalloid solution, 25 mg diphenhydramine IV
D) Oxygen via nonrebreather mask, IV crystalloid solution, 0.3 mg epinephrine SC, 25 mg diphenhydramine IV, albuterol 2.5 mg via nebulizer