Which of the Following Best Explains the Cause of the Histamine

Which of the following best explains the cause of the histamine and heparin release in response to exposure to an antigen?

A) Humoral cells have initiated a chemical attack on the antigens.
B) IgE antibodies have attached themselves to the membranes of basophils and mast cells, resulting in degranulation.
C) IgG and IgM antibodies have activated basophils and mast cells, resulting in degranulation.
D) IgE antibodies have activated the membranes of B and T cells, resulting in release of histamine and heparin.