Which of the following explains the profound protein catabolism and gluconeogenesis associated with Cushing's syndrome?
A) Cushing's syndrome affects normal fat deposition.
B) Glucocorticoids cause sodium retention and increased blood volume.
C) Cortisol is an antagonist to insulin.
D) Increased epinephrine and norepinephrine release result in hypermetabolism.

Question

Quizplus · Accepted Answer

Cortisol is an antagonist to insulin, which leads to increased gluconeogenesis and protein catabolism. This is a major contributing factor to the symptoms of Cushing's syndrome.

Which of the Following Explains the Profound Protein Catabolism and Gluconeogenesis