The continued use of the drug despite the fact that it may be harmful and serves no medical purpose is:

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The continued use of a drug despite harm and no medical benefit is a hallmark sign of addiction. Substance abuse refers to the use of drugs in a way that is harmful or hazardous, but may not necessarily involve addiction. Withdrawal refers to the physical and psychological symptoms experienced when stopping or reducing use of a drug. Habituation refers to a person becoming accustomed to a drug or behavior, but does not necessarily involve harmful or compulsive use.

The Continued Use of the Drug Despite the Fact That