The relative therapeutic effectiveness of chemically comparable drugs is regarded as the:
A) bioassay of the drugs.
B) relative efficacy of the drugs.
C) bioequivalence.
D) therapeutic index.

Question

Quizplus · Accepted Answer

Bioequivalence refers to the similarity in the bioavailability of different pharmaceutical formulations of the same drug. It indicates that there is no significant difference in the rate and extent of active ingredient absorption from a pharmaceutical equivalent product compared to another. Therefore, the relative therapeutic effectiveness of chemically comparable drugs can be evaluated by their bioequivalence. Choice A (bioassay of the drugs) refers to the measurement of the potency of a drug by comparing its effects on a living organism with those of a reference standard. Choice B (relative efficacy of the drugs) refers to the ability of a drug to produce a therapeutic effect in a specific population or with a particular disease or condition. Choice D (therapeutic index) refers to the margin of safety of a drug, calculated by dividing its lethal dose by its effective dose.

The Relative Therapeutic Effectiveness of Chemically Comparable Drugs Is Regarded