Please put the following steps of Cap synthesis in the correct order.(1)N⁷ of the capping guanine is methylated.(2)The terminal phosphate is removed from the pre-mRNA.(3)A capping GMP is added to the pre-mRNA.(4)The 2'O-methyl group of the penultimate nucleotide is methylated.

Question

Quizplus · Accepted Answer

The correct order for cap synthesis is: (2) removal of the terminal phosphate from the pre-mRNA, (3) addition of a capping GMP to the pre-mRNA, (1) methylation of the capping guanine, and (4) methylation of the penultimate nucleotide. This sequence ensures the proper modification of the mRNA cap structure, which is crucial for mRNA stability and initiation of translation.

Please Put the Following Steps of Cap Synthesis in the Correct