The catalytic center of the spliceosome appears to include

Question

Quizplus · Accepted Answer

The catalytic center of the spliceosome includes Mg²⁺, U2 and U6 snRNP, and the branch point region of the intron. These components work together to catalyze the splicing reaction, removing the intron and joining the exons. Mg²⁺ provides the catalytic metal ions, U2 snRNP recognizes the branch point sequence and helps position the splice site, U6 snRNP stabilizes the active site and participates in catalysis, and the branch point region of the intron serves as the nucleophile in the splicing reaction.

The Catalytic Center of the Spliceosome Appears to Include