The Histone Code states that the

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The Histone Code hypothesis proposes that the combination of histone modifications (such as acetylation, methylation, phosphorylation, etc.) on a given nucleosome can affect the accessibility of DNA for transcription factors and RNA polymerase, ultimately affecting the efficiency of transcription of nearby genes. This hypothesis does not suggest that the primary sequence of histone proteins never changes, or that histone modifications affect the transcription of all nearby genes equally. The Histone Code also includes modifications to other amino acids besides lysine. While histones are common in many eukaryotic cells, they are not found in all living cells (such as bacteria).

The Histone Code States That the