Predict the effect of blocking GTPase activity by a mutant lacking the GAP gene.Which of the following would be a possible outcome if cells in this mutant are treated with a growth factor?

Question

Quizplus · Accepted Answer

Blocking GTPase activity by a mutant lacking the GAP gene would result in sustained activation of transduction pathways, as GTPase activity is required for turning off or inactivating these pathways. Therefore, even in the presence of a growth factor, the transduction pathway would continue to be active, resulting in sustained signaling and ultimately leading to cell growth and proliferation. The other options do not directly relate to the effect of blocking GTPase activity and are therefore not likely outcomes.

Predict the Effect of Blocking GTPase Activity by a Mutant