Predict What May Occur When Two Separate Operators Are Bound

Predict what may occur when two separate operators are bound to molecules of a specific repressor.

A) attraction of other repressors to the site
B) cooperative binding of a second repressor
C) looping out of the intervening nonoperator sequence
D) attraction of other repressors to the site and cooperative binding of a second repressor
E) cooperative binding of a second repressor and looping out of the intervening nonoperator sequence