Osteoporosis can result from excessive production of receptor activator of nuclear factor $ \kappa $ light-chain enhancer of activated B cells (RANK)ligand (RANKL)by osteoblasts.A molecule that directly inhibits RANKL and protects bones from osteoclast overactivity is:

Question

Quizplus · Accepted Answer

Osteoprotegerin (OPG) is a molecule that directly inhibits RANKL, which is responsible for osteoclast overactivity. By inhibiting RANKL, OPG can protect bones from excessive osteoclast activity and prevent osteoporosis. PTH, alkaline phosphatase, osteoid, and RANK are not direct inhibitors of RANKL and do not have the same protective effect on bones.

Osteoporosis Can Result from Excessive Production of Receptor Activator of Nuclear