Mineralocorticoid antagonists such as spironolactone (Aldactone)and eplerenone (Inspra)are used primarily:

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Mineralocorticoid antagonists are primarily used as diuretics in treating hypertension and heart failure. They work by blocking the action of aldosterone, a hormone that causes the kidneys to retain sodium and water. By blocking this hormone, these drugs promote the excretion of sodium and water, leading to a reduction in blood volume and therefore blood pressure. While they may have some anti-inflammatory effects, they are not primarily used as such, and they are not used as immunosuppressants. Additionally, while they may be used in some cases of adrenocortical insufficiency, they are not typically used as replacement therapy for this condition.

Mineralocorticoid Antagonists Such as Spironolactone (Aldactone)and Eplerenone (Inspra)are Used Primarily