Phosphodiesterase inhibitors such as inamrinone (generic)and milrinone (Primacor)may help increase myocardial contraction in heart failure by ______ the breakdown of cyclic adenosine monophosphate (cAMP),which leads to a(n)______ in calcium in cardiac cells.

Question

Quizplus · Accepted Answer

Phosphodiesterase inhibitors work by inhibiting the breakdown of cAMP, leading to increased cAMP levels, which enhances calcium influx into cardiac cells, thereby increasing myocardial contraction.

Phosphodiesterase Inhibitors Such as Inamrinone (Generic)and Milrinone (Primacor)may Help Increase