To avoid the first-pass effect,nitroglycerin can be administered:

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Quizplus · Accepted Answer

Nitroglycerin can bypass the first-pass effect by being administered sublingually, buccally, or via transdermal patches. Sublingual and buccal administration allows the drug to enter the systemic circulation directly through the oral mucosa, while transdermal patches deliver the drug through the skin and into the bloodstream. This bypasses the liver and allows for more of the drug to reach its intended target, resulting in a more potent and effective response. Therefore, all three options are viable choices to avoid the first-pass effect.

To Avoid the First-Pass Effect,nitroglycerin Can Be Administered