Patients taking relatively high doses of the more potent antipsychotics may experience catatonia,stupor,rigidity,tremors,and fever.These symptoms comprise a serious disorder known as:

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The symptoms listed, including catatonia, stupor, rigidity, tremors, and fever, are all indicative of neuroleptic malignant syndrome (NMS), a serious and potentially fatal disorder that can occur in patients taking high doses of potent antipsychotics. Treatment for NMS includes discontinuing the antipsychotic medication and providing supportive care.

Patients Taking Relatively High Doses of the More Potent Antipsychotics