Clinical assessment of a lesion reveals a severe hypersensitivity reaction, with the lips and tongue especially affected. Additionally, "bull's eye" or "target eye" skin lesions are present, and the onset of all lesions was abrupt or "explosive." The condition is most likely:

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Erythema multiforme is possibly caused by a hypersensitivity reaction with an acute onset. The bull ' s -eye description of the skin lesions is very characteristic .

Clinical Assessment of a Lesion Reveals a Severe Hypersensitivity Reaction