Highly effective vaccines have been produced. Why can't we seem to develop an effective vaccine for HIV?
A) The best protective effect would be a stimulation of antibodies from B cells and production of infected cell killing cytotoxic CD8+ T cells, most likely from a live attenuated form of HIV used as a vaccine. Both of these cell types require the help of CD4+ helper T cells. HIV infects and destroys the very cells required to produce a strong protective immune response to a vaccine (CD4+ helper T cells) . This would make the use of a live, attenuated virus as a vaccine impractical.
B) HIV goes latent quite quickly in every one of the cells it infects. This latency makes it extremely difficult to completely eradicate from an individual, even if a protective immune response were able to be induced by a vaccine.
C) HIV vaccines of any kind would be far too dangerous to test on human beings. Without human testing, we can't be sure of their effectiveness in order to begin using them for human protection.
D) The best protective effect would be achieved solely by production of anti-HIV antibodies from B cells. However, B cells become infected with HIV and are destroyed. A vaccine would destroy the very cells we need to stimulate to best fight the infection.
Correct Answer:
Verified
Q58: Cytomegalovirus is a(n)
A) enveloped double-stranded DNA virus.
B)
Q59: Mycobacterium avium complex organisms
A) survive phagocytosis.
B) are
Q60: Which of the following is typically used
Q61: HIV may induce rapid cell division in
Q62: The vast majority of Mycobacterium avium complex
Q63: What is the best reason (most useful
Q64: How might the progression of HIV have
Q65: Live vaccines are generally unsafe to give
Q66: If AIDS was present in Africa in
Q68: A CDC epidemiologist presents a report to
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents