C S Is a 28-Year-Old Woman Diagnosed with Rheumatoid Arthritis 2

C. S. is a 28-year-old woman diagnosed with rheumatoid arthritis 2 years previously. She has periods of relatively mild joint stiffness and pain interspersed with periods of increased symptom severity. A clinical finding consistent with C. S.'s diagnosis of rheumatoid arthritis would be

A) systemic manifestations of inflammation.
B) localized pain in weight-bearing joints.
C) reduced excretion of uric acid by the kidney.
D) firm, crystallized nodules or "tophi" at the affected joints.