Glutamate can damage neurons when it accumulates in synapses after brain injury because it opens calcium channels.

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Glutamate is an excitatory neurotransmitter that can cause damage to neurons if it accumulates in excessive amounts in the synapse. This is especially problematic after brain injury because glutamate can activate calcium channels, leading to an influx of calcium ions into the neuron, which can ultimately cause cell death.

Glutamate Can Damage Neurons When It Accumulates in Synapses After