A patient with renal disease is at risk for developing uremia as his nephrons progressively deteriorate because

Question

Quizplus · Accepted Answer

As the nephrons deteriorate, the glomerular filtration rate (GFR) declines, leading to a buildup of waste products and toxins in the blood, which is known as uremia. Choice A is incorrect because an increasingly permeable basement membrane is not a characteristic of renal disease. Choice B is incorrect because filtration alone does not cause uremia, and the secretory and reabsorptive capacity of the nephrons are also affected by renal disease. Choice C is also incorrect because excessive solute and water loss in the urine would actually lead to dehydration, not uremia.

A Patient with Renal Disease Is at Risk for Developing